Smart drug delivery systems: back to the future vs. clinical reality.

Smart drug delivery systems: back to the future vs. clinical reality.
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DOI:
10.1016/j.ijpharm.2013.02.046
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发表时间:
2013-09-15
影响因子:
5.8
通讯作者:
Lammers, Twan
Lammers, Twan
中科院分区:
医学2区
文献类型:
--
作者:
Lammers, Twan

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纳米技术和材料科学的最新进展重新点燃了人们对药物递送研究的兴趣。然而,可以说,几乎没有任何开发的系统和提出的策略是真正相关的塑造未来(临床)面对纳米医学领域。因此,正如这篇评论中所概述的那样,我们不应该制造更多的载体材料,使纳米医学成为科幻小说和虚构科学,我们应该尝试提出合理和现实的概念,使纳米医学发挥作用,特别是在患者身上。
Recent advances in nanotechology and material science have re-ignited interest in drug delivery research. Arguably, however, hardly any of the systems developed and strategies proposed are really relevant for shaping the future (clinical) face of the nanomedicine field. Consequently, as outlined in this commentary, instead of making ever more carrier materials, and making nanomedicine both science-fiction and fiction-science, we should try to come up with rational and realistic concepts to make nanomedicines work, in particular in patients.
DOI: 10.1016/j.ijpharm.2013.02.020
发表时间: 2013-09-15
影响因子: 5.8
作者:
Crommelin, Daan J. A.;Florence, Alexander T.
通讯作者: Florence, Alexander T.