Synthesis of aromatic aldehydes by organocatalytic [4+2] and [3+3] cycloaddition of α,β-unsaturated aldehydes
Synthesis of aromatic aldehydes by organocatalytic [4+2] and [3+3] cycloaddition of α,β-unsaturated aldehydes
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DOI：
10.1016/j.tet.2007.01.039
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发表时间：
2007-03-26
期刊：
影响因子：
2.1
通讯作者：
Chen, Shang-Hung
中科院分区：
文献类型：
--
作者：
Hong, Bor-Cherng;Tseng, Hsing-Chang;Chen, Shang-Hung
描述了α，β-不饱和醛的有机催化分子间和分子内[4+2]和[3+3]环加成反应，得到多取代芳香醛。在L-脯氨酸和吡咯烷-HOAc的催化作用下，环加成反应具有较高的介电选择性，同时还观察到了助催化剂和相加作用。(C)2007爱思唯尔有限公司。保留所有权利。
Organocatalytic inter- and intramolecular [4+2] and [3+3] cycloadditions of alpha,beta-unsaturated aldehydes to give polysubstituted aromatic aldehydes are described. High periselectivity for the cycloadditions, with catalyst effects exerted by L-proline and pyrrolidine-HOAc, as well as cocatalyst, additive effects, has been observed. (c) 2007 Elsevier Ltd. All rights reserved.