A review of the impact of obesity on common gastrointestinal malignancies.
A review of the impact of obesity on common gastrointestinal malignancies.
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DOI：
10.15761/icst.1000223
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Conwell DL
中科院分区：
文献类型：
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作者：
Krishna SG;Hussan H;Cruz-Monserrate Z;Conteh LF;Mumtaz K;Conwell DL
肥胖是一种全球性流行病，是各种胃肠道疾病的公认危险因素。所有年龄组的肥胖症发病率都在增加。迫切需要有针对性的指导方针，旨在减少肥胖的发病率，患病率和相关风险。肥胖对胃肠道癌症的影响是多因素的，对相关风险、病程、预后和总生存率产生不利影响。我们总结了目前的文献，强调肥胖和常见的胃肠道癌症之间的关联，特别关注食管腺癌，结肠癌，肝细胞癌，胆管癌和胰腺恶性肿瘤。
Obesity is a global pandemic and is a well-recognized risk factor for various gastrointestinal diseases. The prevalence of obesity is increasing across all age groups. There is an emergent need for focused guidelines aimed at reducing the incidence, prevalence, and associated risks of obesity. The impact of obesity on gastrointestinal cancers being multifactorial adversely influences the associated risk, disease course, prognosis, and overall survival. We have summarized the current literature highlighting the association between obesity and common gastrointestinal cancers, with specific focus on esophageal adenocarcinoma, colon cancer, hepatocellular cancer, cholangiocarcinoma, and pancreatic malignancies.