Effects of Oral Branched-Chain Amino Acids (BCAAs) Intake on Muscular and Central Fatigue During an Incremental Exercise
Effects of Oral Branched-Chain Amino Acids (BCAAs) Intake on Muscular and Central Fatigue During an Incremental Exercise
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DOI：
10.2478/hukin-2019-0099
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发表时间：
2020-03-01
影响因子：
2.3
通讯作者：
Al-Abdulla, Zainalabidden
中科院分区：
文献类型：
--
作者：
AbuMoh'd, Mohammad Fayiz;Matalqah, Laila;Al-Abdulla, Zainalabidden
本研究的目的是调查的影响，口服支链氨基酸（支链氨基酸）摄入量对肌肉（肌酸激酶和肌红蛋白）和中央（5-羟色胺）疲劳在递增运动方案，并确定时间耗尽。16名男性长跑运动员（25.7 +/- 2.0岁）进行了两次试验，间隔14天。采用双盲、安慰剂对照、随机交叉设计，参与者在跑步机上进行递增运动前1小时摄入20 g BCAA（BCAA试验）或安慰剂。起始速度为8 km/h，每5分钟增加1 km/h，直到意志力耗尽。血液分析表明，BCAA试验中血清素的血浆水平（259.3 +/- 13.5 ng/ml）低于安慰剂试验（289.1 +/- 14.5 ng/ml）（p < 0.05）。游离脂肪酸的结果模式相似（p < 0.05）。BCAA试验中的肌酸激酶水平（346.1 +/- 33.7 U/L）高于安慰剂试验（307.3 +/- 30.2 U/L）。在肌红蛋白水平方面，未观察到试验之间的显著差异（p = 0.139）。在BCAA试验中（50.4 +/- 2.3分钟），至筋疲力尽的时间比安慰剂试验（46.6 +/- 3.2分钟）长。总之，在递增跑步机运动前1小时口服20 g支链氨基酸增加了至力竭的时间，这可能是由于血清素浓度降低。由于肌红蛋白水平在两项试验中均在正常范围内，我们得出结论，参与者没有达到肌肉疲劳。
The aim of this study was to investigate the effects of oral branched-chain amino acids (BCAAs) intake on muscular (creatine kinase and myoglobin) and central (serotonin) fatigue during an incremental exercise protocol and to determine the time to exhaustion. Sixteen male long-distance runners (25.7 +/- 2.0 yrs) performed two trials, 14 days apart. Using a double-blind, placebo-controlled, randomised crossover design, participants ingested either 20 g of BCAAs (BCAA trial) or a placebo 1 hour prior to performing an incremental exercise session on a treadmill. The starting speed was 8 km/h and this was increased by 1 km/h every 5 minutes until volitional exhaustion. Blood analysis indicated that plasma levels of serotonin were lower in the BCAA trial (259.3 +/- 13.5 ng/ml) than the placebo trial (289.1 +/- 14.5 ng/ml) (p < 0.05). There was a similar pattern of results for free fatty acid (p < 0.05). The creatine kinase level was higher in the BCAA trial (346.1 +/- 33.7 U/L) than the placebo trial (307.3 +/- 30.2 U/L). No significant difference between trials was observed regarding the level of myoglobin (p = 0.139). Time to exhaustion was longer in the BCAA trial (50.4 +/- 2.3 min) than the placebo trial (46.6 +/- 3.2 min). In conclusion, oral intake of 20 g of BCAAs 1 hour prior to an incremental treadmill exercise session increased time to exhaustion, probably due to the reduction in serotonin concentration. As myoglobin levels were within the normal range in both trials, we conclude that the participants did not reach muscular fatigue.