Evaluation of the effective connectivity of supplementary motor areas during motor imagery using Granger causality mapping
Evaluation of the effective connectivity of supplementary motor areas during motor imagery using Granger causality mapping
复制标题
使用格兰杰因果图评估运动想象期间辅助运动区域的有效连接
DOI：
10.1016/j.neuroimage.2009.06.026
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发表时间：
2009-10-01
期刊：
影响因子：
5.7
通讯作者：
Shen, Shan
中科院分区：
文献类型：
--
作者：
Chen, Huafu;Yang, Qin;Shen, Shan
多年来，人们对运动想象过程中的大脑激活进行了广泛的研究，但这些研究中只有少数关注于调查大脑中的有效连接。在运动想象过程中，SMA和其他脑区之间是否存在相互作用或闭合回路尚不清楚。在本研究中，我们选择SMA作为感兴趣的区域，使用格兰杰因果关系映射（GCM）方法来探索运动成像过程中大脑的有效连接。我们的研究结果表明，在进行右手运动想象时，与左手运动想象时相比，更多的大脑区域显示出与SMA的有效连接，但左手运动想象时的随意影响强度比右手运动想象时强。我们进一步发现，SMA与双侧背侧运动前区（PMd）、对侧初级和次级体感皮层（S1）以及初级运动皮层（M1）三个区域之间存在正向和向后的有效连接。这些结果可能表明在运动想象过程中大脑区域是如何相互激活的。(C) 2009爱思唯尔公司版权所有
Brain activation during motor imagery has been studied extensively for years, but only a few of these studies focused on investigating the effective connectivity in the brain. The existence of interactions or closed loop circuits between the SMA and other brain regions during motor imagery still remains unclear. In the present study, selecting the SMA as the region of interest, we used the Granger causality mapping (GCM) method to explore the effective connectivity in the brain during motor imagery. Our results demonstrated that more brain regions showed effective connections to the SMA during the right-hand motor imagery than during the left-hand motor imagery, but the strength of the casual influence during the left-hand motor imagery was stronger than that of the right-hand motor imagery. We further found forward and backward effective connectivity between the SMA and three regions, including the bilateral dorsal premotor area (PMd), the contralateral primary and secondary somatosensory cortex (S1), and the primary motor cortex (M1). these results might indicate how the brain regions were inter-activated during motor imagery. (C) 2009 Elsevier Inc. All rights reserved