Effects of a 48-h fast on heart rate variability and cortisol levels in healthy female subjects
Effects of a 48-h fast on heart rate variability and cortisol levels in healthy female subjects
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DOI：
10.1038/ejcn.2013.32
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发表时间：
2013-04-01
影响因子：
4.7
通讯作者：
Enck, P.
中科院分区：
文献类型：
--
作者：
Mazurak, N.;Guenther, A.;Enck, P.
背景/证据：无论禁食的原因是什么（例如，医疗、生活方式、宗教、政治或饥荒），禁食期间发生的生理变化都尚未完全了解。本研究的目的是研究48小时的影响，对心率变异性（HRV）和皮质醇水平在健康的年轻女性volunteers.SUBJECTS/METHODS：共16名年轻健康女性志愿者进行了48小时的总禁食下24小时的医疗监督。在入院时（第1天）、禁食24小时（第2天）和禁食48小时（第3天）测量心理（主观饥饿感）和生理数据（HRV、昼夜皮质醇曲线）。结果：从第1天到第3天测量的体重减轻导致所有受试者的体重指数（BMI）显著降低（P
BACKGROUND/OBJECTIVES: The physiological changes that occur during fasting are not completely understood, regardless of the cause for fasting (for example, medical, lifestyle, religious, political or famine). The purpose of this study was to examine the effects of a 48-h fast on heart rate variability (HRV) and cortisol levels in healthy young female volunteers.SUBJECTS/METHODS: A total of 16 young healthy female volunteers underwent 48 h of total fasting under 24-h medical surveillance. Psychological (subjective feeling of hunger) as well as physiological data (HRV, diurnal cortisol profiles) were measured upon admission (Day 1), and after 24 (Day 2) and 48 h (Day 3) of fasting.RESULTS: There was a measured weight loss from Day 1 to Day 3 that resulted in significant body mass index (BMI) reduction across all subjects (P