Colchicine myopathy in a patient with familial Mediterranean fever and normal renal function.
Colchicine myopathy in a patient with familial Mediterranean fever and normal renal function.
复制标题
患有家族性地中海热且肾功能正常的患者的秋水仙碱肌病。
DOI:
10.1002/art.11185
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发表时间:
2003
期刊:
影响因子:
--
通讯作者:
Merkel,PeterA
中科院分区:
文献类型:
--
作者:
Kissin,EugeneY;Corbo,JosephC;Farraye,FrancisA;Merkel,PeterA
Patients with familial Mediterranean fever (FMF) routinely take large daily doses of colchicine to both prevent and abort acute attacks (1, 2) and to reduce the risk of developing amyloidosis (3). Unfortunately, colchicine can also cause a number of toxic side effects, including neuromyopathy. Almost all cases of colchicine neuromyopathy previously described have been associated with renal insufficiency (4). We report the first case of biopsy-confirmed myopathy due to chronic colchicine administration in an adult with FMF and normal renal function.