Thyroid function at diagnosis of type I diabetes

Thyroid function at diagnosis of type I diabetes
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DOI:
10.1136/adc.2009.168799
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发表时间:
2011-08-01
影响因子:
5.2
通讯作者:
Blair, J.
Blair, J.
中科院分区:
医学2区
文献类型:
--
作者:
Joseph, J.;Saroha, V.;Blair, J.

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国家指南建议在诊断I型糖尿病(TIDM)时评估甲状腺功能,此后每年评估一次。本文报告了根据这一指南对110例TIDM患者(男性66例)进行的2.3(0.7-4.2)年的甲状腺监测结果,其中21/110例(19.0%)患者在TIDM诊断时甲状腺功能异常。其中,16例在45(3-540)天后重新评估时甲状腺功能正常。糖尿病酮症酸中毒(DKA)患儿甲状腺功能减退发生率明显高于非DKA患儿(9/29,31.0%vs12/81,14.8%,p
Background National guidelines recommend that thyroid function is assessed at diagnosis of type I diabetes (TIDM) and annually thereafter. This paper reports an audit of thyroid surveillance in accordance with this guideline.Patients 110 patients (66 males), median age 11.3 (1.2-15.7) years at diagnosis of TIDM, were monitored for 2.3 (0.7-4.2) years.Results 21/110 (19.0%) patients had abnormal thyroid function at diagnosis of TIDM. Of these, 16 had normal thyroid function on reassessment after 45 (3-540) days. Abnormalities of thyroid function occurred more commonly in children with diabetic ketoacidosis (DKA) than those who did not have DKA (9/29, 31.0% vs 12/81, 14.8%, p