Update on the global spread of dengue
Update on the global spread of dengue
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DOI：
10.1016/j.ijantimicag.2010.06.018
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发表时间：
2010-11-01
影响因子：
10.8
通讯作者：
Isturiz, Raul E.
中科院分区：
文献类型：
--
作者：
Guzman, Alfonso;Isturiz, Raul E.
登革热在通常的热带边界内外的全球传播威胁着世界上很大一部分人口，因为各大洲都存在导致登革热持续存在甚至传播的人类和环境条件。这种疾病给人类造成巨大痛苦，登革出血热及其并发症造成相当大的死亡率，并造成重大损失。这种情况最近有所恶化，今后可能还会继续恶化。通过病媒控制减少传播的努力失败了，目前没有有效的抗病毒治疗，也无法预见近期的情况。迫切需要一种安全有效的疫苗来预防所有血清型的登革热病毒。(C) 2010 Elsevier B.V.与International Society of Chemotherapy。版权所有。
The global spread of dengue fever within and beyond the usual tropical boundaries threatens a large percentage of the world's population, as human and environmental conditions for persistence and even spread are present in all continents. The disease causes great human suffering, a sizable mortality from dengue haemorrhagic fever and its complications, and major costs. This situation has worsened in the recent past and may continue to do so in the future. Efforts to decrease transmission by vector control have failed, and no effective antiviral treatment is available or foreseeable on the immediate horizon. A safe and effective vaccine protective against all serotypes of dengue viruses is sorely needed. (C) 2010 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.