HOW A CIGARETTE IS SMOKED DETERMINES BLOOD NICOTINE LEVELS

HOW A CIGARETTE IS SMOKED DETERMINES BLOOD NICOTINE LEVELS
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DOI:
10.1038/clpt.1983.12
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发表时间:
1983-01-01
影响因子:
6.7
通讯作者:
MINES, AH
MINES, AH
中科院分区:
医学2区
文献类型:
--
作者:
HERNING, RI;JONES, RT;MINES, AH

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吸低焦油和尼古丁香烟并不一定会减少对这些物质的接触。当11名受试者吸2支或4支香烟时,测量了抽吸量、持续时间和次数、抽吸间隔、吸入量和持续时间。吸烟前后测量尼古丁血液水平和呼气CO。机器测定的香烟尼古丁产量与吸烟后尼古丁血液水平的增加相关(r = 0.52),但当吸烟行为的个体差异与尼古丁产量沿着考虑时,与尼古丁血液水平的相关性更强(r = 0.84-0.93)。
Smoking low-tar and nicotine cigarettes does not necessarily reduce exposure to these substances. Puff volume, duration and number, interpuff interval and volume and duration of inhalation were measured while 11 subjects smoked 2 or 4 tobacco cigarettes. Nicotine blood levels and breath CO were measured before and after smoking. The machine-determined nicotine yields of the cigarettes correlated (r = 0.52) with the increase in nicotine blood levels after smoking, but when individual differences in smoking behavior were taken into account along with the nicotine yield, there was a stronger correlation with nicotine blood levels (r = 0.84-0.93).