Arterial spin-labeling MR imaging in moyamoya disease compared with clinical assessments and other MR imaging finings
Arterial spin-labeling MR imaging in moyamoya disease compared with clinical assessments and other MR imaging finings
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DOI：
10.1016/j.ejrad.2013.08.040
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发表时间：
2013-12-01
影响因子：
3.3
通讯作者：
Irie, Hiroyuki
中科院分区：
文献类型：
--
作者：
Noguchi, Tomoyuki;Kawashima, Masatou;Irie, Hiroyuki
目的：我们的目的是通过比较ASL-MRI与Moyamoya disease.Methods的临床信息和其他MRI表现，确定与ASL-MRI获得的灌注分布的因果因素：71例Moyamoya disease患者进行了ASL-MRI和其他MRI，包括液体衰减反转恢复成像（FLAIR）和三维飞行时间磁共振血管造影（MRA）在3.0特斯拉MRI系统。在ASL-MRI生成的CBF图上测量大脑半球（142侧）的脑血流量（CBF）值（ASL值）。评估ASL值与以下9个因素的关系：性别、家族史、血管重建术、MR检查时年龄、发病年龄、MRA狭窄闭塞程度（MRA评分）、基底侧支循环程度、FLAIR上软脑膜高信号程度、缺血性或出血性脑血管意外病变大小结果：有家族史的患者ASL值明显高于无家族史的患者。ASL值与MR检查时的年龄、MRA评分和CVA评分之间呈显著负相关。结论：ASL-MRI可能与Moyamoya病的家族史、当前患者年龄、CVA病变大小和颅内动脉狭窄闭塞严重程度有因果关系或相互关联。(C)2013爱思唯尔爱尔兰有限公司版权所有。
Purpose: Our purpose was to identify the causal factors for the perfusion distribution obtained with ASL-MRI by comparing ASL-MRI with clinical information and other MRI findings in moyamoya disease.Methods: Seventy-one patients with moyamoya disease underwent ASL-MRI and other MRI, including fluid-attenuated inversion recovery imaging (FLAIR) and three-dimensional time-of-flight magnetic resonance angiography (MRA) on 3.0-Tesla MRI system. Cerebral blood flow (CBF) values (ASL values) for the cerebral hemispheres (142 sides) were measured on CBF maps generated by ASL-MRI. Relationships between the ASL values and the following 9 factors were assessed: sex, family history, revascularization surgery, age at MR exam, age at onset, the steno-occlusive severity on MRA (MRA score), degree of basal collaterals, degree of leptomeningeal high signal intensity seen on FLAIR, and size of ischemic or hemorrhagic cerebrovascular accident lesion (CVA score).Results: Patients with a family history had significantly higher ASL values than those without such a history. There were significant negative correlations between ASL values and age at MR exam, MRA score, and CVA score.Conclusions: ASL-MRI may have cause-and-effect or mutual associations with family history, current patient age, size of CVA lesion, and intracranial arterial steno-occlusive severity in Moyamoya disease. (C) 2013 Elsevier Ireland Ltd. All rights reserved.