Draft Genome Sequence of the Tumor-Targeting Salmonella enterica Serovar Typhimurium Strain SL7207.
Draft Genome Sequence of the Tumor-Targeting Salmonella enterica Serovar Typhimurium Strain SL7207.
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DOI：
10.1128/genomea.01591-16
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发表时间：
2017-02-02
期刊：
影响因子：
--
通讯作者：
Wall DM
中科院分区：
文献类型：
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作者：
Johnson SA;Ormsby MJ;Wall DM
鼠伤寒沙门氏菌菌株SL 7207是菌株SL 1344的遗传修饰衍生物，其优先在肿瘤中积累，并且可用作体内组织特异性基因递送的载体。在这里，我们报告了SL7207的基因组序列草图，证实了与SL1344相比的aroA缺失和四个单核苷酸多态性。
Salmonella enterica serovar Typhimurium strain SL7207 is a genetically modified derivative of strain SL1344, which preferentially accumulates in tumors and can be used as a vehicle for tissue-specific gene delivery in vivo. Here, we report the draft genome sequence of SL7207, confirming a purported aroA deletion and four single-nucleotide polymorphisms compared to SL1344.