Eddy current compensated double diffusion encoded (DDE) MRI
Eddy current compensated double diffusion encoded (DDE) MRI
复制标题
涡流补偿双扩散编码 (DDE) MRI
DOI：
10.1002/mrm.26092
复制
发表时间：
2015
影响因子：
3.3
通讯作者：
Laun FB
中科院分区：
文献类型：
--
作者：
Müller L;Wetscherek A;Kuder TA;Laun FB
目的涡流可能会导致扩散加权平面回波成像中的图像失真。提出了一种方法来减小它们对双扩散编码磁共振实验的影响以及由此产生的微观分数各向异性(μFA)。为了评估单个扩散编码对图像失真的影响，对水中的塑料棒网格进行了测量。在6名健康志愿者的大脑中评估了涡流补偿对μFA测量的影响。正如预期的那样，第二次编码造成的失真比第一次编码的大，因此需要更强烈地对其进行补偿。然而，为了获得最佳结果，必须对这两种编码进行补偿。伪影减少通过减少高估，大大改善了脑室和灰质μFA的测量。未观察到补偿对脑白质μFA值绝对值的影响。结论在测量涡流时，建议对两种编码进行补偿。Magn Reson Med 77：328-335,2017。©2015 Wiley期刊，Inc.
PurposeEddy currents might lead to image distortions in diffusion‐weighted echo planar imaging. A method is proposed to reduce their effects on double diffusion encoding (DDE) MRI experiments and the thereby derived microscopic fractional anisotropy (μFA).MethodsThe twice‐refocused spin echo scheme was adapted for DDE measurements. To assess the effect of individual diffusion encodings on the image distortions, measurements of a grid of plastic rods in water were performed. The effect of eddy current compensation on μFA measurements was evaluated in the brains of six healthy volunteers.ResultsThe use of an eddy current compensation reduced the signal variation. As expected, the distortions caused by the second encoding were larger than those of the first encoding, entailing a stronger need to compensate for them. For an optimal result, however, both encodings had to be compensated. The artifact reduction strongly improved the measurement of the μFA in ventricles and gray matter by reducing the overestimation. An effect of the compensation on absolute μFA values in white matter was not observed.ConclusionIt is advisable to compensate both encodings in DDE measurements for eddy currents. Magn Reson Med 77:328–335, 2017. © 2015 Wiley Periodicals, Inc.
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