Examining the role of menthol cigarettes in progression to established smoking among youth
Examining the role of menthol cigarettes in progression to established smoking among youth
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DOI：
10.1016/j.addbeh.2019.106045
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发表时间：
2019-11-01
影响因子：
4.4
通讯作者：
Rass, Olga
中科院分区：
文献类型：
--
作者：
Nonnemaker, James;Feirman, Shari P.;Rass, Olga
背景：薄荷醇是一种添加到香烟中的香料化合物，它使香烟对年轻人和缺乏经验的吸烟者更具吸引力，并增加了香烟的滥用倾向。然而，关于薄荷醇在吸烟进展中的作用的研究有限。方法：为了评估香烟中的薄荷醇与吸烟进展之间的关联，我们使用了青少年烟草队列研究公共教育活动评估的五波数据，这是一项具有全国代表性的对美国年轻人的纵向调查，作为“真实成本”评估的一部分。我们使用离散时间生存分析，以薄荷醇使用指标作为关键解释变量，使用Logit模型对两个事件结果的发生进行建模-进展到已确定的、当前吸烟，以及进展到已确定的、频繁吸烟。基于这个框架，我们估计了以前使用薄荷醇对吸烟进展的影响。结果：在建立的当前吸烟模型的进展中，以前使用薄荷醇与吸烟进展显著相关[调整后的优势比(AOR)=1.80，p<；0.05，可信区间(CI)=(1.03-3.16)]。虽然研究结果与已建立的频繁吸烟进展模型的趋势相似，但以前使用薄荷醇与这一进展模型之间的关联并未达到显著水平[AOR=1.56，CI=(0.80-3.03)]。结论：本研究结果提示，在青少年中，使用薄荷醇香烟与从实验性吸烟到现有吸烟的进展有关。这项研究增加了越来越多的文献基础，支持薄荷醇香烟与非薄荷醇香烟相比，增加了年轻人经常吸烟的风险。
Background: Menthol, a flavoring compound added to cigarettes, makes cigarettes more appealing to youth and inexperienced smokers and increases cigarettes' abuse liability. However, limited studies are available on menthol's role in smoking progression.Methods: To assess the association between menthol in cigarettes and progression to established smoking, we used five waves of data from the Evaluation of Public Education Campaign on Teen Tobacco Cohort Study, a nationally representative longitudinal survey of U.S. youth conducted as part of "The Real Cost" evaluation. We used discrete time survival analysis to model the occurrence of two event outcomes-progression to established, current smoking and progression to established, frequent smoking-using a logit model with a menthol use indicator as the key explanatory variable. Based on this framework, we estimated the effect of prior menthol use on the odds of smoking progression.Results: In the progression to established, current smoking model, prior menthol use was significantly associated with progression [adjusted odds ratio (aOR) = 1.80, p < .05, confidence interval (CI) = (1.03-3.16)]. While results were in a similar direction for the model of progression to established, frequent smoking, the association between prior menthol use and this progression model did not reach significance [aOR = 1.56, CI = (0.80-3.03)].Conclusion: The results suggest a relationship between using menthol cigarettes and progression from experimental to established, current smoking among youth. This study adds to a growing literature base that supports that menthol cigarettes, compared to nonmenthol cigarettes, put youth at increased risk for regular cigarette use.