AN ANTIEMETIC PRINCIPLE OF PINELLIA-TERNATA TUBER
AN ANTIEMETIC PRINCIPLE OF PINELLIA-TERNATA TUBER
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DOI：
10.1055/s-2006-962759
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发表时间：
1987-10-01
期刊：
影响因子：
2.7
通讯作者：
SHIBATA, S
中科院分区：
文献类型：
--
作者：
MAKI, T;TAKAHASHI, K;SHIBATA, S
从半夏（Pinellia ternata（Thunb.）白令，一种中药，作为一种止吐的原则。对豹蛙和蛙类口服阿扑吗啡的催吐作用有拮抗作用。通过Sephacryl S-300和TSK-G4000 SW柱上的色谱法分离的多糖PT-F2-I，[a]D25：（H2O，c 1），通过13 C-NMR光谱和甲基化分析结合GC-MS进行研究。（1）4)-与α的连接（1）2)-侧链作为主要部分，寡糖链作为亚基，包括比例为0.12、0.1、0.09、0.05和0.05的岩藻糖、葡萄糖、半乳糖、鼠李糖和核糖，条件是阿拉伯糖为1.00。半乳糖醛酸的存在也证明了由咔唑比色法，和钙可能是连接到它是由X射线能谱仪测定。
A polysaccharide fraction was isolated from the aqueous extracts of the tuber of Pinellia ternata (Thunb.) Breit, a Chinese drug, as an anti-emetic principle. It was antagonistic to the emetic action induced by apomorphine by the oral administration to leopard and ranid frogs. The polysaccharide, PT-F2-I, [a]D25: (H2O, c 1), separated by means of chromatography over sephacryl S-300 and TSK-G4000SW columns, was studied by the 13C-NMR spectra and methylation analysis combined with GC-MS. PT-F2-I was represented by an arabinan consisting of .alpha. (1 .fwdarw. 4)-linkages with .alpha. (1 .fwdarw. 2)-side chains as the main part, and oligosaccharide chains as the subunits involving fucose, glucose, galactose, rhamnose, and ribose in the ratio of 0.12, 0.1, 0.09, 0.05, and 0.05 provided that arabinose was 1.00. The presence of galacturonic acid was also proved by the carbazol colorimetric method, and calcium which is probably attached to it was determined by an X-ray energy spectrometer.