PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences
PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences
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DOI：
10.1093/nar/30.1.325
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发表时间：
2002-01-01
影响因子：
14.9
通讯作者：
Rombauts, S
中科院分区：
文献类型：
--
作者：
Lescot, M;Déhais, P;Rombauts, S
PlantCare是一个植物顺式作用调控元件、增强子和抑制子的数据库。调控元件由位置矩阵、共有序列和特定启动子序列上的单个位点表示。提供了EMBL、TRANSFAC和MEDLINE数据库的链接。关于转录位点的数据主要从文献中提取，辅之以越来越多的电子预测数据。除了对特定转录因子位点的一般描述外，还给出了实验证据、功能信息和启动子位置的置信度。已经实现了在查询序列中搜索植物顺式作用调控元件的新特征。此外，现在提供了一种新的聚类和基序搜索方法的链接，以研究共表达基因的簇。新的监管要素可以自动发送，并将在管理后添加到数据库中。植物护理关系数据库可通过万维网获得，网址为：http://sphinx.rug.ac.be:8080/PlantCARE/.
PlantCARE is a database of plant cis-acting regulatory elements, enhancers and repressors. Regulatory elements are represented by positional matrices, consensus sequences and individual sites on particular promoter sequences. Links to the EMBL, TRANSFAC and MEDLINE databases are provided when available. Data about the transcription sites are extracted mainly from the literature, supplemented with an increasing number of in silico predicted data. Apart from a general description for specific transcription factor sites, levels of confidence for the experimental evidence, functional information and the position on the promoter are given as well. New features have been implemented to search for plant cis-acting regulatory elements in a query sequence. Furthermore, links are now provided to a new clustering and motif search method to investigate clusters of co-expressed genes. New regulatory elements can be sent automatically and will be added to the database after curation. The PlantCARE relational database is available via the World Wide Web at http://sphinx.rug.ac.be:8080/PlantCARE/.