Ethanol consumption in rats selectively bred for differential saccharin intake
Ethanol consumption in rats selectively bred for differential saccharin intake
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DOI：
10.1016/s0741-8329(98)00010-x
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发表时间：
1998-11-01
期刊：
影响因子：
2.3
通讯作者：
Blizard, DA
中科院分区：
文献类型：
--
作者：
Dess, NK;Badia-Elder, NE;Blizard, DA
选择性培育的高酒精消耗的大鼠品系比低酒精消耗的同类品系消耗更多的糖精溶液。本研究利用相互选择技术来检验糖精/乙醇关系的可靠性；具体地说，在选择性培育的高VS、低糖精消耗的大鼠(西方His系和LOS系)中测量了1-10%乙醇溶液的消耗量。他的老鼠比洛杉矶的老鼠消耗更多的酒精。这些结果支持了乙醇和糖精消费的个体差异具有共同机制的观点(S)。(C)1998年爱思唯尔科学公司。
Rat lines selectively bred for high ethanol consumption consume more saccharin solution than do their low-ethanol-consuming counterparts. The present study utilized the technique of reciprocal selection to examine the reliability of the saccharin/ethanol relationship; specifically, consumption of 1-10% ethanol solution was measured in rats selectively bred for high vs, low saccharin consumption (Occidental HiS and LoS lines). HiS rats consumed more ethanol than did LoS rats. These results support the idea that individual differences in ethanol and saccharin consumption share some common mechanism(s). (C) 1998 Elsevier Science Inc.