The Treatment of Pathologic Gambling
The Treatment of Pathologic Gambling
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DOI：
10.1097/adt.0b013e31803155c2
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发表时间：
2008-03-01
影响因子：
1.1
通讯作者：
Potenza, Marc N.
中科院分区：
文献类型：
--
作者：
Brewer, Judson A.;Grant, Jon E.;Potenza, Marc N.
目的：综述循证行为和药物治疗在病理性赌博（PG）治疗中的应用。方法：回顾现有文献，总结和评价行为和药物治疗研究的结果。结果：多种行为和药物治疗在PG治疗中已被研究。与不治疗相比，几种类型的行为治疗似乎对PG的治疗有益。对于那些参加的人来说，自助计划似乎是有帮助的。在药物治疗中，选择性5-羟色胺再摄取抑制剂显示出混合的结果，而阿片类拮抗剂显示出更一致的疗效，尽管对这些药物进行的研究较少。其他药物治疗已显示出初步的积极成果。摘要：多种行为和药物治疗已被研究，并显示在治疗PG的承诺。更大的研究，更长的随访是必要的。针对PG患者特定亚群的治疗可能会改善和提高特定治疗的疗效，标准化的结局指标应改善研究间干预措施的比较。
Objective:To review evidence-based behavioral and pharmacologic therapies in the treatment of pathologic gambling (PG).Methods:Available literature was reviewed and results of behavioral and pharmacologic treatment studies were summarized and evaluated.Results:Multiple behavioral and pharmacologic therapies have been studied in the treatment of PG. Compared with no treatment, several types of behavioral treatments seem beneficial in the treatment of PG. For those who attend, self-help programs seem helpful. Among pharmacotherapies, selective serotonin reuptake inhibitors have shown mixed results whereas opioid antagonists have shown more consistent efficacy, although fewer studies have been performed with these agents. Other pharmacotherapies have shown preliminary positive results.Summary:Multiple behavioral and pharmacologic therapies have been studied and show promise in the treatment of PG. Larger studies with longer follow-up are needed. Treatments targeting specific sub-populations of people with PG will likely refine and enhance efficacies of specific therapies, and standardized outcome measures should improve comparisons of interventions across studies.