Clinical Study on Treatment of Hyperuricaemia by Retention Enema of Chinese Herbal Medicine Combined with Allopurinol

Clinical Study on Treatment of Hyperuricaemia by Retention Enema of Chinese Herbal Medicine Combined with Allopurinol
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DOI:
10.1007/s11655-009-0431-2
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发表时间:
2009-12-01
影响因子:
2.9
通讯作者:
Wupu, Akebaier
Wupu, Akebaier
中科院分区:
医学3区
文献类型:
--
作者:
Chen Qian;Ma Li;Wupu, Akebaier

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目的:探讨中药保留灌肠联合别嘌醇治疗高尿酸血症的疗效。方法:将78例HUE患者随机分为两组,治疗组40例采用中药保留灌肠配合口服别嘌醇治疗,对照组38例单用别嘌醇治疗。两组疗程均为6周。观察两组的临床疗效、症状变化、血尿酸、血脂、肾功能、24 h尿微量白蛋白。结果:治疗组总有效率为92.5%,明显高于对照组的68.4%(P
Objective: To study the effect of retention enema of Chinese herbal medicine combined with allopurinol in treating hyperuricaemia (HUE). Methods: Seventy-eight patients with HUE were assigned to two groups, the 40 patients in the treated group were treated with retention enema of Chinese herbal medicine combined with oral intake of allopurinol, and the 38 patients in the control group were treated with allopurinol alone. The therapeutic course for all was 6 weeks. The clinical efficacy, changes of symptoms, blood levels of uric acid and lipids, renal function, and 24 h urinary micro-albumin were observed. Results: The total effective rate was 92.5% in the treated group, which was significantly higher than that in the control group (68.4%, P