Coordination of cranial motoneurons during mastication
Coordination of cranial motoneurons during mastication
复制标题
DOI：
10.1016/j.resp.2005.02.017
复制
发表时间：
2005-07-28
影响因子：
2.3
通讯作者：
Inoue, M
中科院分区：
文献类型：
--
作者：
Yamada, Y;Yamamura, K;Inoue, M
咀嚼是消化的第一阶段，涉及几个运动过程，如食物摄入、口腔内食物运输、食团形成和广义上的咀嚼。这些复杂的运动功能可以通过支配下颌、舌骨、舌和面部肌肉的各种颅运动神经元的协调活动来完成。脑干咀嚼中枢模式发生器（CPG）在产生这些颅运动神经元群的基本活动模式中起着至关重要的作用。然而，来自高级大脑的下行输入（例如，大脑皮层）和咀嚼产生的外周感觉输入也在调节每个运动神经元的活动模式中起重要作用，使得最终的运动输出符合环境需求。本文就咀嚼运动过程中三叉神经、面神经和舌下神经运动神经元的协调作用作一综述。我们首先总结的结果显示这些运动神经元支配的肌肉在自然咀嚼的活动模式，然后讨论可能的神经机制，在咀嚼协调活动。(C)2005 Elsevier B.V.保留所有权利。
Mastication is the first stage of digestion and involves several motor processes such as food intake, intra-oral food transport, bolus formation and chewing in its broad sense. These complicated motor functions can be accomplished by the well-coordinated activities in various cranial motoneurons innervating the jaw, hyoid, tongue and facial muscles. The brainstem masticatory central pattern generator (CPG) plays a crucial role in generating basic activity patterns of these cranial motoneuron groups. However, descending inputs from higher brain (e.g., cerebral cortex) and mastication-generated peripheral sensory inputs also play important roles in modulating the activity pattern of each motoneuron so that the final motor outputs fit the environmental demand. In this review, we focus on the coordination of the trigeminal, facial and hypoglossal motoneurons during mastication. We first summarize findings showing the activity patterns of muscles innervated by these motoneurons during natural mastication, and then discuss the possible neural mechanisms underlying their coordinated activities during mastication. (C) 2005 Elsevier B.V. All rights reserved.