Congenital Chagas Disease: Estimating the Potential Risk in the United States
Congenital Chagas Disease: Estimating the Potential Risk in the United States
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DOI：
10.4269/ajtmh.2009.09-0257
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发表时间：
2009-12-01
影响因子：
3.3
通讯作者：
Schmunis, Gabriel A.
中科院分区：
文献类型：
--
作者：
Yadon, Zaida E.;Schmunis, Gabriel A.
经济困难和/或政治动荡刺激了受克氏锥虫感染的人口从拉丁美洲国家向美国和欧洲迁移;查加斯病的原始病例通过血液、器官捐赠和垂直传播传播。1990年和2000年，来自南美锥虫病流行国家的西班牙裔育龄妇女移民分别为2 384 644人和5 841 538人。考虑到T.根据1990年和2000年我国新生儿克氏锥虫感染率分别为85-318例和166-638例，估计我国新生儿克氏锥虫感染率分别为1.33%和5%。需要对处于危险中的母亲和新生儿进行感染诊断。当后代早期治疗时，治愈率几乎达到100%。卫生当局、专业协会、医生和西班牙裔群体应该更多地关注这个问题。
Economic hardship and/or political turmoil stimulated migration of Trypanosoma cruzi-infected population from Latin American countries to the United States and Europe; originating cases of Chagas disease were transmitted through blood, organ donation, and vertical transmission. Hispanic immigrant women of reproductive age ill the United States coming from Chagas disease-endemic countries accounted for 2,384,644, and 5,841,538 in 1990 and 2000, respectively. Considering the prevalence rates for T. cruzi infection in their country of origin and the risk of newborns from infected mothers to acquire congenital infection as 1.33% and 5%, we estimated that the number of T cruzi-infected newborns was 85-318 in 1990 and 166-638 in 2000. Diagnosis of infection in the mother and newborns at risk is needed. A high rate of cure is achieved, almost 100%, when the offspring is treated early. Health authorities, professional associations, physicians, and Hispanic groups should pay more attention to the subject.