Loneliness in psychotic disorders and its association with cognitive function and symptom profile

Loneliness in psychotic disorders and its association with cognitive function and symptom profile
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DOI:
10.1016/j.schres.2015.10.027
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发表时间:
2015-12-01
影响因子:
4.5
通讯作者:
Morgan, Vera A.
Morgan, Vera A.
中科院分区:
医学2区
文献类型:
--
作者:
Badcock, Johanna C.;Shah, Sonal;Morgan, Vera A.

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背景资料:孤独感涉及主观而非客观的社会孤立,并对身心功能产生一系列负面影响。本研究的目的是探讨精神障碍患者孤独感的患病率及其与症状和认知能力的关系。数据来自第二次澳大利亚国家精神病调查,包括1642名国际疾病分类10诊断为精神障碍的参与者的回答,他们完成了症状和社会功能的半结构化访谈(包括孤独),沿着当前(数字符号编码; DSC)和发病前(国家成人阅读测试)认知能力的标准化评估。我们研究了孤独的患病率在精神病的诊断类别,其与精神病性和非精神病性症状和数字符号编码scores.Results:孤独的患病率很高,范围从74.75%的参与者与妄想症的93.8%,抑郁性精神病,是显着高于一般人群。孤独症还与快感缺乏和主观思维障碍显著相关。与那些偶尔感到孤独的人相比,感到社交孤立/孤独的参与者的DSC分数显着降低。出乎意料的是,参与者谁不感到孤独有最低的DSC scores.Conclusions:孤独是常见的所有精神障碍,特别是在抑郁性精神病。它特别与持续的快乐和混乱的思想以及当前认知功能的损害有关。然而,认知功能不佳并不一定与孤独有关。个性化治疗精神病的影响进行了讨论。(C)2015 Elsevier B. V.版权所有。
Background: Loneliness involves subjective, rather than objective, social isolation and has a range of negative effects on mental and physical functioning. The purpose of this study was to examine the prevalence of loneliness in psychotic disorders and its association with symptoms and cognitive performance.Method: Data were drawn from the second Australian National Survey of Psychosis and comprised responses from 1642 participants with an International Classification of Diseases 10 diagnosis of psychotic disorder who had completed a semi-structured interview of symptoms and social functioning (including loneliness), along with standardized assessments of current (digit symbol coding; DSC) and premorbid (National Adult Reading Test) cognitive ability. We examined the prevalence of loneliness across the diagnostic categories of psychosis, and its association with psychotic and non-psychotic symptoms and digit symbol coding scores.Results: The prevalence of loneliness was high, ranging from 74.75% in participants with delusional disorders to 93.8% in depressive psychosis, and was significantly higher than in the general population. Loneliness was also significantly associated with anhedonia and subjective thought disorder. Participants feeling socially isolated/lonely for company had significantly lower DSC scores than those who only felt lonely occasionally. Unexpectedly, participants who reported not feeling lonely had the lowest DSC scores.Conclusions: Loneliness is common across all psychotic disorders, particularly in depressive psychosis. It is specifically associated with ongoing loss of pleasure and disordered thoughts as well as impairment in current cognitive functioning. However, poor cognitive functioning is not inevitably associated with loneliness. Implications for personalized treatment of psychosis are discussed. (C) 2015 Elsevier B.V. All rights reserved.