The MicrobesOnline web site for comparative genomics
The MicrobesOnline web site for comparative genomics
复制标题
DOI：
10.1101/gr.3844805
复制
发表时间：
2005-07-01
期刊：
影响因子：
7
通讯作者：
Arkin, AP
中科院分区：
文献类型：
--
作者：
Alm, EJ;Huang, KH;Arkin, AP
目前，已有数百个微生物基因组测序，还有数百个正在进行中。微生物压力和生存虚拟研究所开发了一套公开可用的基于网络的比较基因组工具（http://www.microbesonline.org），旨在促进原核生物之间的多物种比较。MicrobesOnline网站的亮点包括操纵子和调控子预测、多物种基因组浏览器、多物种基因本体浏览器、比较KEGG代谢途径查看器、用于深度序列分析的生物信息学工作台，以及允许用户在浏览时保存感兴趣的基因以供进一步研究的基因购物车。此外，我们提供了基因组注释的接口，就像这里报道的所有工具一样，对科学界免费提供。
At present, hundreds of microbial genomes have been sequenced, and hundreds more are currently in the pipeline. The Virtual Institute for Microbial Stress and Survival has developed a publicly available Suite of Web-based comparative genomic tools (http://www.microbesonline.org) designed to facilitate multispecies comparison among prokaryotes. Highlights of the MicrobesOnline Web site include operon and regulon predictions, a multispecies genome browser, a multispecies Gene Ontology browser, a comparative KEGG metabolic pathway viewer, a Bioinformatics Workbench for in-depth sequence analysis, and Gene Carts that allow users to save genes of interest for further study while they browse. In addition, we provide an interface for genome annotation, which like all of the tools reported here, is freely available to the scientific community.