UK release of genetically marked virus

UK release of genetically marked virus
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英国释放带有基因标记的病毒

DOI:
10.1038/323496a0
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发表时间:
1986
期刊:
影响因子:
64.8
通讯作者:
D. Bishop
D. Bishop
中科院分区:
综合性期刊1区
文献类型:
--
作者:
D. Bishop

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作者报告说,在考虑了安全性问题并与有关当局协商后,最近在英国的一块‘卷心菜地’生态系统中释放了一种带有基因标记的杆状病毒。母体病毒--管状多角体病毒,是美国注册的杀虫剂。在田间用网状化合物对感染了标记病毒的夜蛾幼虫进行了有限的释放,以防止宿主的扩散或与其他昆虫或捕食者的相互作用,从而限制了病毒的扩散和相互作用的机会。这项研究的生态目标是精确测量病毒在所用生态系统中持续存在的能力。总体目的是制定关于在环境中使用基因工程制剂的风险评估案例研究。结果将在数据分析后公布。
The author reports the recent experimental release of a genetically-marked baculovirus in a 'cabbage-patch' ecosystem in the UK after consideration of the safety aspects and in consultation with the relevant authorities. The parent virus,Autographa californicanuclear polyhedrosis virus, is a registered insecticide in the USA. A limited release of larvae ofSpodoptera exiguainfected with the marked virus was made in a field in a netted compound that prevented the dispersal of the host or its interaction with other insects or predators, thereby restricting dispersal and the opportunity for viral amplification and interaction. The ecological object of the study was to measure precisely the ability of the virus to persist in the ecosystem used. The overall purpose was to develop a risk assessment case study on the use of genetically-engineered agents in the environment. The results are to be published when the data have been analysed.