Effects of a low phosphorus, low nitrogen diet supplemented with essential amino acids and ketoanalogues on serum triglycerides of chronic uremic patients.
Effects of a low phosphorus, low nitrogen diet supplemented with essential amino acids and ketoanalogues on serum triglycerides of chronic uremic patients.
复制标题
补充必需氨基酸和酮类似物的低磷、低氮饮食对慢性尿毒症患者血清甘油三酯的影响。
作者：
F. Ciardella;E. Morelli;F. Niosi;R. Caprioli;R. Baldi;A. Cupisti;G. Petronio;C. Carbone;G. Barsotti
研究了补充必需氨基酸和酮类似物的低蛋白、低磷素食饮食以及维持性血液透析 (MHD) 和自由饮食对 85 名慢性肾功能衰竭患者血清甘油三酯 (STG) 的影响。饮食治疗后，61 名男性患者的 STG 显着下降（从 185.7 +/- 89.8 至 153.5 +/- 68.7 mg/dl；p 小于 0.001），而女性患者的下降并不显着（从 189.1 +/- 83.9 至 167.0 +/- 62.2 mg/dl；NS）。当患者改为MHD治疗和自由饮食时STG再次升高。我们可以得出结论，纠正慢性男性尿毒症性腺功能减退症在很大程度上是高甘油三酯血症改善的原因，尽管其他因素也可能有所贡献。
The effects were studied of a vegetarian low-protein, low-phosphorus diet supplemented with essential amino acids and ketoanalogues and those of maintenance hemodialysis (MHD) and free diet on the serum triglycerides (STG) of 85 patients with chronic renal failure. Following dietary therapy STG decreased significantly in the 61 male patients (from 185.7 +/- 89.8 to 153.5 +/- 68.7 mg/dl; p less than 0.001), whereas in the females the decrease was not significant (from 189.1 +/- 83.9 to 167.0 +/- 62.2 mg/dl; NS). When patients changed to MHD therapy and free diet STG increased again. We can conclude that the correction of hypogonadism of chronic male uremics largely accounts for the improvement of hypertriglyceridemia, though other factors are likely to contribute.