Low prevalence of smoking in patients with autism spectrum disorders
Low prevalence of smoking in patients with autism spectrum disorders
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DOI：
10.1016/s0165-1781(03)00123-9
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发表时间：
2003-07-15
影响因子：
11.3
通讯作者：
Nylander, L
中科院分区：
文献类型：
--
作者：
Bejerot, S;Nylander, L
精神病患者比一般人群更经常吸烟，唯一已知的例外是强迫症（OCD）和紧张性精神分裂症。我们调查了自闭症谱系障碍（ASD）受试者的尼古丁使用情况。95名连续诊断为任何ASD且智力正常的受试者（25名女性和70名男性）被纳入研究。只有12.6%的人是吸烟者，相比之下，普通人群中吸烟者的比例为19%，而在161名被诊断为精神分裂症或精神分裂症样障碍的门诊患者中，吸烟者的比例为47%。结果表明，吸烟在ASD患者中很少见，而精神分裂症患者则相反。如果重复，这一发现可能表明非紧张性精神分裂症和ASD之间的生物学差异，并支持ASD和强迫症亚型之间以及ASD和紧张性精神分裂症之间存在生物学联系的理论。(C)2003爱思唯尔爱尔兰有限公司保留所有权利。
Psychiatric patients are significantly more often smokers than the general population, the only known exception being obsessive-compulsive disorder (OCD) and catatonic schizophrenia. We have investigated nicotine use in subjects with autism spectrum disorders (ASD). Ninety-five subjects (25 females and 70 males) consecutively diagnosed with any ASD and of normal intelligence were included in the study. Only 12.6% were smokers, compared with 19% in the general population and 47% in a control group of 161 outpatients diagnosed with schizophrenia or a schizophreniform disorder. The results suggest that smoking is rare among subjects with ASD, while the opposite was shown for schizophrenia. If replicated, this finding could suggest biological differences between non-catatonic schizophrenia and ASD, and support the theory of a biological link between ASD and a subtype of OCD, and between ASD and catatonic schizophrenia. (C) 2003 Elsevier Ireland Ltd. All rights reserved.