MEASUREMENT OF HUMAN-FETAL BLOOD-FLOW
MEASUREMENT OF HUMAN-FETAL BLOOD-FLOW
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DOI：
10.1136/bmj.280.6210.283
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发表时间：
1980-01-01
影响因子：
--
通讯作者：
ULSTEIN, MK
中科院分区：
文献类型：
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作者：
EIKNES, SH;BRUBAKK, AO;ULSTEIN, MK
实时b超结合脉冲多普勒超声技术经皮测量人胎儿主动脉和腹腔内脐静脉血流。在二维实时图像中定位目标血管并测量其直径。脉冲多普勒换能器以固定角度与实时换能器连接。仪器通过对多普勒频移信号的处理，估计出平均流速和最大流速以及流速曲线下的积分。这样就可以计算血流量。该方法应用于26例正常妊娠晚期胎儿。胎儿主动脉降段以最大流速计算的平均血流量为191 ml/kg/min。腹腔内脐静脉平均流量为110 ml/kg/min。这种测量方法是非侵入性的，为研究胎儿血流动力学开辟了新的视角。
Real-time B-mode ultrasonography was combined with a pulsed Doppler ultrasound technique for transcutaneous measurement of human fetal blood flow in the aorta and intra-abdominal part of the umbilical vein. The target vessel was located and its diameter measured in the two-dimensional real-time image. The pulsed Doppler transducer was attached to the real-time transducer at a fixed angle. By processing the Doppler shift signals the instrument estimated the mean and maximum blood velocities and the integral under the velocity curves. This permitted calculation of the blood flow. The method was applied to 26 fetuses in normal late pregnancies. Mean blood flow in the descending part of the fetal aorta based on maximum velocity was 191 ml/kg/min. Mean flow in the intra-abdominal part of the umbilical vein was 110 ml/kg/min. This method of measurement is non-invasive and opens new perspectives in studying fetal haemodynamics.