Different types of inflammatory reactions in peri-implant soft tissues.
Different types of inflammatory reactions in peri-implant soft tissues.
复制标题
种植体周围软组织的不同类型的炎症反应。
DOI：
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发表时间：
2005
影响因子：
6.7
通讯作者：
Björn Klinge
中科院分区：
文献类型：
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作者：
I. Ericsson;L. Persson;T. Berglundh;Carlo P. Marinello;J. Lindhe;Björn Klinge
本研究的目的是分析犬模型中暴露于斑块积聚长达9个月的部位的植入物周围粘膜的一些特征。实验在5只拉布拉多犬中进行。拔除下颌左右第2、3、4前磨牙（2 P2、3 P3、4P 4）和第1磨牙（1 M1）。3个月愈合期后，在无牙前磨牙/磨牙区域安装3个钛固定装置（Nobelpharma AB，Göteborg，Sweden）。3个月后进行基台连接，并开始了3个月的细致菌斑控制期。在该准备期结束时进行临床检查，并继续9个月的主研究期。在此期间，在近中和中央（左侧：L1，2和右侧：R1，2）种植体节段中维持斑块控制方案，而允许斑块在远端种植体上积累，即。L3和R3。在主要研究期结束时，即，基台连接后12个月，重复临床检查，动物灌注和活检。制作半薄切片进行组织学和形态学分析。在活检时暴露于每日和全面斑块控制的植入部位的植入物周围粘膜在临床上无炎症，连接上皮侧面的结缔组织没有炎症细胞积聚。（250字处删节）
The aim of the present study was to analyze some features of the peri-implant mucosa at sites in the dog model which had been exposed to plaque accumulation for periods up to 9 months. The experiment was carried out in 5 labrador dogs. The mandibular right and left 2nd, 3rd and 4th premolars (2P2, 3P3, 4P4) and the 1st molars (1M1) were extracted. Following a 3-month healing period, 3 titanium fixtures (Nobelpharma AB, Göteborg, Sweden) were installed in the edentulous premolar/molar regions. Abutment connection was performed 3 months later and a meticulous plaque control period of 3 months was initiated. A clinical examination was performed at the end of this preparatory period and a main study period of 9 months continued. During this period, the plaque control regimen was maintained in the mesial and central (left: L1, 2 and right: R1, 2) implant segments, whereas plaque was allowed to accumulate on the distal implants, i.e.. L3 and R3. At the end of the main study period, i.e., 12 months after abutment connection, the clinical examination was repeated, the animals perfused and biopsies obtained. Semi-thin sections were produced for histometric and morphometric analyses. The peri-implant mucosa at implant sites exposed to daily and comprehensive plaque control at biopsy was clinically noninflamed and the connective tissue lateral to a junctional epithelium was devoid of accumulations of inflammatory cells.(ABSTRACT TRUNCATED AT 250 WORDS)