KINETICS OF HUMAN RENIN AND HUMAN SUBSTRATE REACTION
KINETICS OF HUMAN RENIN AND HUMAN SUBSTRATE REACTION
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DOI：
10.1093/cvr/5.1.86
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发表时间：
1971-01-01
影响因子：
10.8
通讯作者：
GREEN, D
中科院分区：
文献类型：
--
作者：
GOULD, AB;GREEN, D
作者简介人肾素水解人肾素底物的米氏常数(Km)为0·931 n-mole/ml。该底物浓度高于血压正常人群中的底物浓度。由于 Kmis 在数值上等于允许反应以其最大速度的一半进行的底物浓度，因此正常血清中的底物浓度出现在非常临界的水平。
Authors' synopsisThe Michaelis constant (Km) for the hydrolysis of human renin substrate by human renin is 0·931 n-mole/ml. This concentration of substrate is higher than that found in a normotensive population. Since the Kmis numerically equal to the concentration of substrate that will permit the reaction to proceed at half its maximal velocity, substrate concentration in normal serum occurs at a very critical level.