The effects of wing bud extirpation on the development of the central nervous system in chick embryos
The effects of wing bud extirpation on the development of the central nervous system in chick embryos
复制标题
DOI：
10.1002/jez.1400680305
复制
发表时间：
1934-08-01
影响因子：
--
通讯作者：
Hamburger, V
中科院分区：
文献类型：
--
作者：
Hamburger, V
为研究外周野对脊髓发育的影响，在72小时鸡胚中摘除右翅芽，5-6天后检查神经系统。第13-16臂神经脊神经节体积发育不全37- 54%。脊髓的右半部分比左半部分小得多。细胞计数显示蚂蚁中有明显的发育不全。还有邮报号角.脊髓的中间部分不受影响。对外周场与C. N. S.通过比较两个系统中的定量变化来接近。蚂蚁体内细胞的数量。角的变化与手术区域肌肉质量的实际损失密切相关。肌肉的缺失率为96%~ 31%，相应的运动神经元发育不良率为61%~ 22%。这一事实表明，每一个周边领域控制着自己的神经中枢的数量发展。
To study the influence of the peripheral fields on the development of the spinal cord, the right wing bud was extirpated in 72-hr. chick embryos, and the nervous system examined 5-6 days later. The spinal ganglia of brachial nerves 13-16 show a hypoplasia in volume of 37-54%. The right half of the spinal cord is considerably smaller than the left. Cell counts revealed a marked hypoplasia in the ant. and the post. horn. The median part of the spinal cord is not affected. The problem of the mechanism of the embryonic correlation between the peripheral fields and the C. N. S. was approached by comparing the quantitative variations in both systems. The number of cells in the ant. horn varies in close quantitative relation to the actual loss of the mass of muscles in the operated region. The loss of muscles ranges from 96% to 31%, the hypoplasia of the corresponding motor neurones ranges from 61% to 22%. This fact suggests that each peripheral field controls the quantitative development of its own nerve center.