Partial rescue of embryos from two maternal-effect neurogenic mutants by transplantation of wild-type ooplasm.
Partial rescue of embryos from two maternal-effect neurogenic mutants by transplantation of wild-type ooplasm.
复制标题
通过移植野生型卵质从两种母体效应神经源性突变体中部分拯救胚胎。
DOI：
10.1016/0012-1606(85)90084-3
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发表时间：
1985
影响因子：
2.7
通讯作者：
Mahowald,AP
中科院分区：
文献类型：
--
作者：
LaBonne,SG;Mahowald,AP
我们发现，母系效应神经性突变的纯合子果蝇产生的胚胎可以通过显微注射野生型卵子部分挽救。此外，我们证明这些突变在这项检测中完全互补，就像他们通过经典的遗传标准所做的那样。最后，我们发现两种突变的胚胎在合胞胚层建立后不再可挽救。讨论了这些结果对我们理解神经源性表型的意义。
We show that embryos produced byDrosophilafemales homozygous for the maternal-effect neurogenic mutationsalmondexandpecanexcan be partially rescued by microinjection of wild-type ooplasm. In addition, we demonstrate that these mutations fully complement one another with respect to this assay, as they do by classical genetic criteria. Finally, we show that embryos from both mutations cease to be rescuable after the establishment of the syncytial blastoderm. The significance of these results for our understanding of the neurogenic phenotype is discussed.