Association Between the Presence of Iron Deficiency Anemia and Hemoglobin A1c in Korean Adults The 2011-2012 Korea National Health and Nutrition Examination Survey
Association Between the Presence of Iron Deficiency Anemia and Hemoglobin A1c in Korean Adults The 2011-2012 Korea National Health and Nutrition Examination Survey
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DOI：
10.1097/md.0000000000000825
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发表时间：
2015-05-01
期刊：
影响因子：
1.6
通讯作者：
Kim, Dong-Jun
中科院分区：
文献类型：
--
作者：
Hong, Jae W.;Ku, Cheol R.;Kim, Dong-Jun
很少有研究探讨缺铁性贫血（IDA）对使用糖化血红蛋白（HbA1c）作为糖尿病或前驱糖尿病筛查参数的临床影响。我们调查了韩国成人中IDA和HbA1c水平之间的关系。参与2011-2012年韩国国民健康与营养调查（韩国疾病控制中心卫生统计进行的一项具有全国代表性的横断面调查）的11472名成年人（>= 19岁）中，807名目前正在服用抗糖尿病药物的糖尿病患者被排除在本研究之外。我们根据空腹血糖（FPG）水平和有无IDA比较了>= 5.7%、>= 6.1%和>= 6.5%的加权HbA1c水平和加权HbA1c水平比例（%）。在10,665名参与者（加权n = 35,229,108）中，贫血和IDA的患病率分别为7.3%和4.3%。IDA患者的HbA1c水平（5.70% +/- 0.02%）高于正常患者（5.59% +/- 0.01%）
Few studies have investigated the clinical effect of iron deficiency anemia (IDA) on the use of the Hemoglobin A1c (HbA1c) as a screening parameter for diabetes or prediabetes. We investigated the association between IDA and HbA1c levels in Korean adults.Among the 11,472 adults (>= 19 years of age) who participated in the 2011-2012 Korea National Health and Nutrition Examination Survey (a cross-sectional and nationally representative survey conducted by the Korean Center for Disease Control for Health Statistics), 807 patients with diabetes currently taking anti-diabetes medications were excluded from this study. We compared the weighted HbA1c levels and weighted proportion (%) of HbA1c levels of >= 5.7%, >= 6.1%, and >= 6.5% according to the range of fasting plasma glucose (FPG) levels and the presence of IDA.Among 10,665 participants (weighted n = 35,229,108), the prevalence of anemia and IDA was 7.3% and 4.3%, respectively. The HbA1c levels were higher in participants with IDA (5.70% +/- 0.02%) than in normal participants (5.59% +/- 0.01%; P