An in vitro study on spontaneous cervical contractility in the cow during oestrus and diestrus
An in vitro study on spontaneous cervical contractility in the cow during oestrus and diestrus
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DOI：
10.1046/j.1439-0442.2003.00583.x
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发表时间：
2003-11-01
期刊：
影响因子：
--
通讯作者：
Steiner, A
中科院分区：
文献类型：
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作者：
Hirsbrunner, G;Reist, M;Steiner, A
从发情期和间情期屠宰的奶牛中采集颈部平滑肌标本。将纵向和圆形标本固定在器官浴槽中，在平衡时间和2g预负荷后，记录其生理等长收缩力2.5 h。研究了曲线下面积（AUC）、最大振幅（A（max））、平均振幅（A（mean））和最小振幅（A（min））。使用线性混合效应模型对周期阶段之间、肌肉层之间和记录时间段内的差异进行统计学评估。在奶牛中，对于评价的所有变量，宫颈的生理收缩性均随时间显著降低（时间作为连续量表上的协变量）。此外，对于A（max），存在肌层影响的趋势（纵向>环形）。收缩力不受周期阶段的影响。
Cervical smooth muscle specimens were collected from slaughtered cows in oestrus and diestrus. Longitudinal and circular specimens were mounted in organ baths and after equilibration time and 2 g pre-load, their physiologic isometric contractility was recorded for 2.5 h. Area under the curve (AUC), maximal amplitude (A(max)), mean amplitude (A(mean)) and minimal amplitude (A(min)) were studied. Differences between cycle phases, between muscle layers and over the recorded time periods were statistically evaluated using linear mixed-effect models. In the cow, physiologic contractility of the cervix decreased significantly over time for all variables evaluated (time as covariate on a continuous scale). Furthermore, for A(max), there was a tendency for an influence of muscle layer (longitudinal > circular). Contractility was not influenced by cycle phases.