Evaluation of Antioxidant and Antimicrobial Activity of Seaweed (Sargassum sp.) Extract: A Study on Inhibition of Glutathione-S-Transferase Activity
Evaluation of Antioxidant and Antimicrobial Activity of Seaweed (Sargassum sp.) Extract: A Study on Inhibition of Glutathione-S-Transferase Activity
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DOI：
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发表时间：
2008-02
影响因子：
2.2
通讯作者：
J. Patra;S. Rath;K. Jena;V. Rathod;H. Thatoi
中科院分区：
文献类型：
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作者：
J. Patra;S. Rath;K. Jena;V. Rathod;H. Thatoi
研究了马尾藻提取物对DPPH自由基和羟自由基的清除能力、对脂质过氧化反应的抑制作用、对谷胱甘肽-S-转移酶的抑制作用以及对微生物的抑制作用。结果表明，该提取物对DPPH自由基和羟自由基具有一定的清除作用，并具有一定的抑菌活性。此外，还观察到脂质过氧化和谷胱甘肽-S-转移酶活性的抑制。总体结果表明，这种海藻可用于对抗多种疾病，并在食品加工业中用于保存食品。
In the present study, the free radical scavenging potentials (DPPH radical and hydroxyl radical), inhibition of lipid peroxidation, and glutathione-S-transferase and antimicrobial properties of Sargassum sp. extract were investigated. The tested extract exhibited a dose-dependent free radical scavenging action against DPPH radical and hydroxyl radical and antimicrobial activity. In addition, inhibition of lipid peroxidation and glutathione-S-transferase activities were also observed. The overall results have established that this seaweed could be used against several diseases and, in the food processing industry, to preserve foods.