Finite element simulation of fluid dynamics and CO$$_2$$2 gas exchange in the alveolar sacs of the human lung
Finite element simulation of fluid dynamics and CO$$_2$$2 gas exchange in the alveolar sacs of the human lung
复制标题
人肺肺泡囊流体动力学和CO$$_2$$2气体交换的有限元模拟
DOI:
10.1007/s40314-018-0692-5
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发表时间:
2018
影响因子:
2.6
通讯作者:
Obidio Rubio
中科院分区:
文献类型:
--
作者:
Luis J Caucha;Stefan Frei;Obidio Rubio
In this article, we present a numerical framework based on continuum models for the fluid dynamics and the COgas distribution in the alveolar sacs of the human lung during expiration and inspiration, including the gas exchange to the cardiovascular system. We include the expansion and contraction of the geometry by means of the Arbitrary Lagrangian–Eulerian (ALE) method. For discretisation, we use equal-order finite elements in combination with pressure-stabilisation techniques based on local projections or interior penalties. We derive formulations for both techniques that are suitable on arbitrarily anisotropic meshes. These formulations are novel within the ALE method. Moreover, we investigate the effect of different boundary conditions, that vary between inspiration and expiration. We present numerical results on a simplified two-dimensional alveolar sac geometry and investigate the influence of the pressure stabilisations as well as the boundary conditions.
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影响因子:
2.9
作者:
J. Lohéac
通讯作者:
J. Lohéac
DOI:
10.1201/9780203904169.ch6
发表时间:
2001
期刊:
arXiv: Analysis of PDEs
影响因子:
--
作者:
R. Dziri;Jean
通讯作者:
Jean
影响因子:
3.3
作者:
FEDERSPIEL, WJ;FREDBERG, JJ
通讯作者:
FREDBERG, JJ
DOI:
10.1016/0034-5687(72)90099-0
发表时间:
1972-01-01
期刊:
RESPIRATION PHYSIOLOGY
影响因子:
--
作者:
HLASTALA, MP
通讯作者:
HLASTALA, MP
DOI:
10.1016/0034-5687(75)90027-4
发表时间:
1975
期刊:
Respiration physiology
影响因子:
--
作者:
P. Kvale;J. Davis;R. Schroter
通讯作者:
R. Schroter