MULTIFREQUENCY BIOELECTRICAL-IMPEDANCE ESTIMATES THE DISTRIBUTION OF BODY-WATER

MULTIFREQUENCY BIOELECTRICAL-IMPEDANCE ESTIMATES THE DISTRIBUTION OF BODY-WATER
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DOI:
10.1152/jappl.1995.79.4.1316
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发表时间:
1995-10-01
影响因子:
3.3
通讯作者:
WILMORE, DW
WILMORE, DW
中科院分区:
医学2区
文献类型:
--
作者:
CHA, KC;CHERTOW, GM;WILMORE, DW

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多频生物电阻抗分析用于估计终末期肾病受试者细胞外水(ECW)与全身水的比例。在1 kHz至1 MHz的频率范围内测量身体的电阻。使用溴化钠稀释液作为比较标准,在低频(5 Mit)下测定的阻抗指数(高度(2)/电阻)与ECW最密切相关(r = 0.886)。与此相反,在高频率(500 kHz)确定的电阻的高度平方的比率与总的身体水分(r = 0.974)使用氧化氘稀释作为比较的标准最密切相关。500 kHz电阻与5 kHz电阻的比值与ECW与总体内水分的比值呈显著正相关(r = 0.767)。多频生物电阻抗分析可以帮助评价终末期肾病和其他液体体积和/或分布的临床疾病中的体内水分分布。
Multifrequency bioelectrical impedance analysis was used to estimate the ratio of extracellular water (ECW) to total body water in subjects with end-stage renal disease. The body's resistance was measured at frequencies ranging from 1 kHz to 1 MHz. The impedance index (height(2)/resistance) determined at low frequency (5 Mit) correlated most closely with ECW (r = 0.886) using sodium bromide dilution as the standard of comparison. In contrast, the ratio of height squared to resistance determined at high frequency (500 kHz) correlated most closely with total body water (r = 0.974) using deuterium oxide dilution as the standard of comparison. The ratio of resistance at 500 kHz to resistance at 5 kHz was directly correlated (r = 0.767) with the ratio of ECW to total body water. Multifrequency bioelectrical impedance analysis may assist in the evaluation of body water distribution in end-stage renal disease and other clinical disorders of fluid volume and/or distribution.