Anxiety State or Masked Depression?
Anxiety State or Masked Depression?
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焦虑状态还是隐性抑郁？
DOI：
10.1192/bjp.119.549.143
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发表时间：
1971
影响因子：
10.5
通讯作者：
J. Young
中科院分区：
文献类型：
--
作者：
J. Pollitt;J. Young
1959 年，West 和 Dally 报告了异丙烟肼对抑郁综合征的作用，引起人们的注意，该药物在“非典型”或“歇斯底里”抑郁状态下的治疗效果比内源性抑郁症更有效。后来，Sargant和Dally（1962）发现了一组以前性格良好、表现出明显抑郁特征的患者，其焦虑症状仅对苯乙肼有反应，但鉴于其他焦虑患者的反应，他们质疑单胺氧化酶抑制剂是否真的具有抗抑郁作用，或者本质上是对抗焦虑的药物。这些发现促成了这项研究，旨在将单胺氧化酶抑制剂引起的焦虑状态的临床表现的其他部分与抑郁症的临床表现进行比较。
In 1959, West and Dally reported the effects of iproniazid in depressive syndromes, drawing attention to the greater therapeutic effectiveness of this drug in ‘atypical’ or ‘hysterical’ depressive states than in endogenous depression. Later, Sargant and Dally (1962) found a group of patients with good previous personalities, showing obvious features of depression, whose anxiety symptoms responded to phenelzine alone, but in view of the response of other patients with anxiety they questioned whether monoamine oxidase inhibitors were really antidepressant, or whether they were essentially drugs acting against anxiety. These findings prompted this study, intended to compare other parts of the clinical pictures of anxiety states responsive to monoamine oxidase inhibitors with those of depressive illnesses.