Lifetime Risk of Acute Myocardial Infarction in Japan

Lifetime Risk of Acute Myocardial Infarction in Japan
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DOI:
10.1161/circoutcomes.109.930776
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发表时间:
2010-11-01
影响因子:
6.9
通讯作者:
Okamura, Tomonori
Okamura, Tomonori
中科院分区:
医学1区
文献类型:
--
作者:
Turin, Tanvir Chowdhury;Kokubo, Yoshihiro;Okamura, Tomonori

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据报道,日本的冠心病(CHD)发病率和死亡率是所有工业化国家中最低的,1,2,但在重大饮食变化和心血管危险因素恶化的背景下,最近的2份报告显示,日本人口中的急性心肌梗死(AMI)有增加的趋势。3、4随着人口老龄化和不利心血管危险因素情景的存在,急性心肌梗死很可能成为日本日益重要的健康负担。因此,急性心肌梗死的预防亟待关注。终生风险(LTR)是一种流行病学测量方法,用来表示某一指标年龄的余生患病概率。提供绝对风险评估的急性心肌梗死的LTR估计在日本人群中还没有报道。在目前的研究中,我们估计了日本人群中急性心肌梗死的短期和中期风险和LTR。
The incidence and mortality from coronary heart disease (CHD) in Japan are reported to be among the lowest of all industrialized countries, 1, 2 but, in the backdrop of major dietary changes and worsening cardiovascular risk factors, 2 recent reports have shown an increasing trend of acute myocardial infarction (AMI) in the Japanese population. 3, 4 With the aging of the population and the presence of unfavorable cardiovascular risk factor scenario, AMI is likely to be an increasingly important health burden in Japan. Thus, prevention of AMI requires urgent attention. Lifetime risk (LTR) is an epidemiological measure that expresses the probability of disease in the remaining lifetime for an index age. Estimation of the LTR of AMI, which provides an absolute risk assessment, has not yet been reported for the Japanese population. In the present study, we estimated the short-and intermediate-term risks and LTR of AMI in a Japanese population.