ATYPICAL ENDOGENOUS FUNGAL ENDOPHTHALMITIS CAUSED BY CANDIDA RUGOSA.
ATYPICAL ENDOGENOUS FUNGAL ENDOPHTHALMITIS CAUSED BY CANDIDA RUGOSA.
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DOI：
10.1097/icb.0000000000001275
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发表时间：
2023-11-01
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我们遇到了一个罕见的情况下，非典型内源性真菌性眼内炎引起的念珠菌皱褶。临床医生有时会遇到由罕见的非白念珠菌引起的侵袭性念珠菌病，使用基本局部比对搜索工具进行DNA分析可有效诊断此类病例。摘要本研究旨在报告一个非典型性内生性真菌性眼内炎的病例，其致病菌为皱褶念珠菌，一种罕见的非白色念珠菌。本报告描述了一个45岁的女性，在乳腺癌治疗期间，除了玻璃体混浊外，右眼视力下降，根据医学检查和病史怀疑为真菌性眼内炎。为诊断进行了各种测试。血液检查结果正常，包括血液β-D-葡聚糖水平，血培养呈阴性。无法使用系统计算机断层扫描和磁共振成像结果进行诊断。因此，通过使用玻璃体切除术收集病变样本。C.使用基本局部比对搜索工具通过DNA（从病变样品中提取）分析鉴定皱纹。右眼的视力在玻璃体切除术后得到改善。我们遇到了一个罕见的情况下，非典型内源性真菌性眼内炎所造成的C。皱纹。临床医生有时会遇到由罕见的非白色念珠菌引起的侵袭性念珠菌病。使用基本局部比对搜索工具的DNA分析对于诊断此类病例是有效的。
We encountered a rare case of atypical endogenous fungal endophthalmitis caused by Candida rugosa. Clinicians sometimes encounter invasive candidiasis caused by rare nonalbicans Candida species, and DNA analysis using Basic Local Alignment Search Tool is effective for diagnosing such cases. The purpose of this study was to report a case of atypical endogenous fungal endophthalmitis caused by Candida rugosa, a rare species of nonalbicans Candida. This report describes a case of a 45-year-old woman who presented with a reduced visual acuity in the right eye in addition to vitreous opacity during breast cancer treatment, which was suspected as fungal endophthalmitis from medical examination and history. Various tests were performed for diagnosis. Blood test results were normal, including the blood beta-D-glucan level, and blood cultures were negative. Diagnosis could not be made using systemic computed tomography and magnetic resonance imaging results. Therefore, a lesion sample was collected by using vitrectomy. C. rugosa was identified through DNA (extracted from the lesion sample) analysis using Basic Local Alignment Search Tool. The visual acuity of the right eye improved after vitrectomy. We encountered a rare case of atypical endogenous fungal endophthalmitis caused by C. rugosa. Clinicians sometimes encounter invasive candidiasis caused by rare nonalbicans Candida species. DNA analysis using Basic Local Alignment Search Tool is effective for diagnosing such cases.