Combined neural and behavioural measures of temporal pitch perception in cochlear implant users
Combined neural and behavioural measures of temporal pitch perception in cochlear implant users
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DOI：
10.1121/1.4934275
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发表时间：
2015-11-01
影响因子：
2.4
通讯作者：
Deeks, John M.
中科院分区：
文献类型：
--
作者：
Carlyon, Robert P.;Deeks, John M.
四个实验测量了几个受试者施加到一个人工耳蜗(CI)电极上的电刺激时间模式的知觉和神经相关性。通过对每个脉冲的电诱发复合动作电位(ECAP)来评估神经效应。实验1对200-PPS脉冲序列中的每秒脉冲进行衰减。衰减的增加导致音调下降，ECAP变得幅度调制，从而提供了神经调制和音调之间的关系的估计。实验2表明，可以通过每秒延迟一次脉冲来减小200-pps脉冲串的音调，从而使脉冲间间隔在更长和更短的间隔之间交替。这导致ECAP变得幅度调制，但幅度不足以解释音调的变化。实验3重复了这一发现，即比率歧视随着基线比率的增加而恶化。这伴随着ECAP调制的增加，但在实验1中，ECAP调制的量对音调只产生了很小的影响。实验4表明，在脉冲序列之前加上精心选择的“预脉冲”可以减少ECAP调制，但不能改善速率辨别力。讨论了对音调理论的启示以及对CI用户音调知觉的限制。(C)2015年作者(S)。除另有说明外，所有文章内容均按照知识共享署名3.0未移植许可进行许可。
Four experiments measured the perceptual and neural correlates of the temporal pattern of electrical stimulation applied to one cochlear-implant (CI) electrode, for several subjects. Neural effects were estimated from the electrically evoked compound action potential (ECAP) to each pulse. Experiment 1 attenuated every second pulse of a 200-pps pulse train. Increasing attenuation caused pitch to drop and the ECAP to become amplitude modulated, thereby providing an estimate of the relationship between neural modulation and pitch. Experiment 2 showed that the pitch of a 200-pps pulse train can be reduced by delaying every second pulse, so that the inter-pulse-intervals alternate between longer and shorter intervals. This caused the ECAP to become amplitude modulated, but not by enough to account for the change in pitch. Experiment 3 replicated the finding that rate discrimination deteriorates with increases in baseline rate. This was accompanied by an increase in ECAP modulation, but by an amount that produced only a small effect on pitch in experiment 1. Experiment 4 showed that preceding a pulse train with a carefully selected "pre-pulse" could reduce ECAP modulation, but did not improve rate discrimination. Implications for theories of pitch and for limitations of pitch perception in CI users are discussed. (C) 2015 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License.