Antioxidant treatment in Spielmeyer‐Sjögren's disease
Antioxidant treatment in Spielmeyer‐Sjögren's disease
复制标题
斯皮尔梅耶-干燥病的抗氧化治疗
DOI：
10.1111/j.1600-0404.1985.tb03178.x
复制
发表时间：
1985
影响因子：
3.5
通讯作者：
Ulla Vuonnala
中科院分区：
文献类型：
--
作者：
P. Santavuori;T. Westermarck;J. Rapola;P. Pohja;Riitta Moren;M. Lappi;Ulla Vuonnala
摘要-提供了125例Spielmeyer-Sjögren病患者的数据。抗氧化治疗49例。27例接受维生素E、维生素C、蛋氨酸和BHT的组合。随着病情的发展，27名患者中有14名患者的治疗改为亚硒酸钠和维生素E的联合治疗。同样的治疗也给予了22名以前没有接受过抗氧化剂补充的儿童。两个治疗组中阳性和阴性应答的数量几乎相等。然而，亚硒酸盐组的反应质量更好，在某些情况下，至少在最初治疗期间开始的恶化可以停止几年。
ABSTRACT – The data for 125 patients with Spielmeyer‐Sjögren's disease is presented. Antioxidant therapy was given to 49. 27 received a combination of vitamin E, vitamin C, methionine and BHT. As the disease began to progress, the treatment was changed to a combintion of sodium selenite and vitamin E in 14 of the 27 patients. The same therapy was also given to 22 children who had not received previous antioxidant supplementation. The number of positive and negative responses was nearly equal in the 2 treatment groups. However, the quality of the response was better in the selenite group and it has been possible in some cases to stop for several years, at least, the deterioration which began during the original therapy.