Survey of hepatitis B knowledge and stigma among chronically infected patients and uninfected persons in Beijing, China
Survey of hepatitis B knowledge and stigma among chronically infected patients and uninfected persons in Beijing, China
复制标题
DOI：
10.1111/liv.13168
复制
发表时间：
2016-11-01
影响因子：
6.7
通讯作者：
Lok, Anna S.
中科院分区：
文献类型：
--
作者：
Huang, Jiaxin;Guan, Mary L.;Lok, Anna S.
背景与目的乙肝病毒感染对中国来说是一种耻辱。方法对北京大学人民医院435例慢性乙型病毒性肝炎患者和801例正常对照进行调查。结果慢性乙型病毒性肝炎患者年龄较大(平均46岁对39岁)，男性多(71%对48%)。慢性乙肝患者的平均知识得分为11.9/15，对照组为9.3/15(P<；0.001)。慢性乙型病毒性肝炎患者的污名评分平均为22.1/39，对照组为19.2/30。控制组对近距离接触(45%)或与CHB患者共餐(39%)表示不适，并认为CHB患者不应被允许在餐馆(58%)或托儿所(44%)工作。与对照组相比，慢性乙肝患者感到自己作为配偶不受欢迎(33%比17%)，并给家人带来麻烦(58%比34%)。尽管法律禁止，但40%的慢性乙肝患者被要求在就业前接受乙肝病毒检测，其中29%的人认为他们因为疾病状况而失去了工作机会。16%的慢性乙型病毒性肝炎患者后悔披露自己的乙肝病毒状况，披露与耻辱呈负相关。在对照组中，较高的污名与年龄较大、文化程度较低、知识得分较低有关；在慢性乙肝患者中，较低的文化程度、较低的年龄、在就业前接受过乙肝病毒检测并后悔透露自己的乙肝状况。结论尽管中国的慢性乙肝患病率较高，但我们的研究表明，人们对乙肝的认识是有限的，而且存在与乙肝病毒感染相关的显著的社会性和内在性污名。
Background & AimsHepatitis B virus (HBV) infection carries substantial stigma in China. We surveyed HBV knowledge and stigma among chronic hepatitis B (CHB) patients and persons without HBV infection in Beijing, China.MethodsFour hundred and thirty five CHB patients and 801 controls at Peking University People's Hospital were surveyed.ResultsChronic hepatitis B patients were older (mean 46 vs. 39 years) and more often men (71 vs. 48%) than controls. Mean knowledge score was 11.9/15 for CHB and 9.3/15 for control patients (P < 0.001). Average stigma score was 22.1/39 for CHB and 19.2/30 for control patients. Controls expressed discomfort with close contact (45%) or sharing meals with CHB patients (39%) and believed CHB patients should not be allowed to work in restaurants (58%) or childcare (44%). Chronic hepatitis B patients felt that they were undesirable as spouses (33 vs. 17%) and brought trouble to their families (58 vs. 34%) more often than controls. Despite legal prohibitions, 40% of CHB patients were required to undergo pre-employment HBV testing, and 29% of these individuals thought that they lost job opportunities because of their disease status. 16% of CHB patients regretted disclosing their HBV status and disclosure was inversely associated with stigma. Higher stigma was associated with older age, lower education and lower knowledge score among controls; and with lower education, younger age, having undergone pre-employment HBV testing and regret disclosing their HBV status among CHB patients.ConclusionDespite high prevalence of CHB in China, our study shows knowledge is limited and there is significant societal and internalized stigma associated with HBV infection.