Body Mass Index Is Better than Other Anthropometric Indices for Identifying Dyslipidemia in Chinese Children with Obesity.
Body Mass Index Is Better than Other Anthropometric Indices for Identifying Dyslipidemia in Chinese Children with Obesity.
复制标题
体重指数比其他人体测量指标更能识别中国肥胖儿童的血脂异常
DOI：
10.1371/journal.pone.0149392
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Jin Y
中科院分区：
文献类型：
--
作者：
Zhu Y;Shao Z;Jing J;Ma J;Chen Y;Li X;Yang W;Guo L;Jin Y
研究背景体重指数（BMI）、腰围（WC）和腰臀比（WHR）是筛查和预测成人肥胖的常用指标。然而，肥胖儿童代谢并发症的最佳标识符仍不清楚。本研究评估了肥胖儿童的血脂分布，并探讨了与血脂紊乱相关的最佳人体测量参数。方法2014年在广州市抽取2243名7-17岁学龄儿童作为研究对象。测量人体测量指标和血脂谱。血脂异常是根据美国儿童和青少年心血管健康和风险降低指南定义的。采用卡方分析和判别函数分析研究人体测量学（BMI、WC和WHR）与血脂水平之间的关系。有关人口统计学，身体活动和饮食摄入量的信息由参与儿童及其父母提供。结果10-14岁和15-17岁儿童甘油三酯水平普遍高于7- 9岁儿童，而总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇的中位数低于7-9岁儿童（均P < 0.001）。这些血脂参数在10-14岁儿童中波动。结合年龄组、BMI、WC和WHR判断血脂异常的准确率为65.1%。BMI对肥胖儿童血脂异常的正确识别率为77%，高于WHR的70.8%（P< 0.05）。结论中国儿童血脂水平在不同年龄组间存在差异，10 ~ 14岁儿童血脂水平波动趋势明显。与其他人体测量指标相比，BMI在识别学龄期肥胖儿童血脂异常方面具有更好的实用性。
Background Body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) are used in screening and predicting obesity in adults. However, the best identifier of metabolic complications in children with obesity remains unclear. This study evaluated lipid profile distribution and investigated the best anthropometric parameter in association with lipid disorders in children with obesity. Methods A total of 2243 school children aged 7–17 years were enrolled in Guangzhou, China, in 2014. The anthropometric indices and lipid profiles were measured. Dyslipidemia was defined according to the US Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents. The association between anthropometry (BMI, WC, and WHR) and lipid profile values was examined using chi-square analysis and discriminant function analysis. Information about demography, physical activity, and dietary intake was provided by the participant children and their parents. Results Children aged 10–14 and 15–17 years old generally had higher triglyceride values but lower median concentration of total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol compared with children aged 7–9 years old (all P < 0.001). These lipid parameters fluctuated in children aged 10–14 years old. The combination of age groups, BMI, WC and WHR achieved 65.1% accuracy in determining dyslipidemic disorders. BMI correctly identified 77% of the total dyslipidemic disorders in obese children, which was higher than that by WHR (70.8%) (P< 0.05). Conclusion The distribution of lipid profiles in Chinese children differed between younger and older age groups, and the tendency of these lipid levels remarkably fluctuated during 10 to 14 years old. BMI had better practical utility in identifying dyslipidemia among school-aged children with obesity compared with other anthropometric measures.