Factors presaging early recurrent myocardial infarction ("extension").
Factors presaging early recurrent myocardial infarction ("extension").
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预示早期心肌梗塞复发（“延伸”）的因素。
DOI：
10.1016/0002-9149(81)90137-5
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Roberts,R
中科院分区：
文献类型：
--
作者：
Marmor,A;Sobel,BE;Roberts,R
对200例连续急性心肌梗死患者进行了前瞻性研究，以描述早期复发性梗死（扩展）的频率和严重程度，表现为继发性血浆MB肌酸激酶（CK）和肌红蛋白峰值，并确定特别高风险的患者。连续MB CK和肌红蛋白测定和连续心电图记录，在所有患者中获得14天，并在选定的患者中获得系列放射性心室造影。胸痛和ST段变化经常发生，分别占整个患者组的57%和43%。然而，仅17%的患者在初次梗死后平均10 ± 4天出现了表明复发性梗死的血浆MB CK水平的继发性升高。43%（25/58）的初次内膜下梗死患者表现为复发性梗死，而初次透壁性梗死患者仅为8%。无早期复发的内膜下梗死患者的死亡率为7%，而复发患者的死亡率为16%。Logistic回归分析表明，肥胖女性患者初始内膜下梗死和反复发作的持续胸痛复发的概率较高（60%），而没有这些特征的患者复发的概率较低（2%）。因此，内膜下梗死后早期再发梗死是常见的，并与死亡率显著增加相关。这些结果表明，内膜下梗死患者复发梗死的风险特别高，这类梗死患者需要严格监测和长期监测。
A prospective study of 200 consecutive patients with acute myocardial infarction was undertaken to characterize the frequency and severity of early recurrent infarction (extension), manifested by secondary plasma MB creatine kinase (CK) and myoglobin peaks, and to identify patients at particularly high risk. Serial MB CK and myoglobin determinations and continuous electrocardiographic recordings were obtained in all patients for 14 days, and serial radioventriculograms were obtained in selected patients. Chest pain and S-T segment changes occurred often, in 57 and 43 percent, respectively, of the entire group of patients. However, a secondary rise in plasma MB CK levels indicative of recurrent infarction, occurring an average of 10 ± 4 days after the initial infarct, was evident in only 17 percent of patients. Forty-three percent (25 of 58) of patients with initial subendocardial infarction exhibited recurrent infarction compared with only 8 percent of those with initial transmural infarction. The mortality rate was 7 percent in patients with subendocardial infarction without early recurrence compared with 16 percent among those with recurrence. Logistic regression analysis indicated that obese women with initial subendocardial infarction and repeated episodes of prolonged chest pain had a high probability rate (60 percent) of recurrence in contrast to the low probability (2 percent) in patients without these features. Thus, early recurrent infarction is frequent after subendocardial infarction and is associated with a marked increase in mortality. These results suggest that patients with subendocardial infarction are at particularly high risk for recurrent infarction and that patients with this type of infarction require vigorous monitoring and prolonged surveillance.
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DOI：
10.1016/0021-9681(71)90106-8
发表时间：
1971-01-01
期刊：
JOURNAL OF CHRONIC DISEASES
影响因子：
--
作者：
HALPERIN, M;BLACKWELDER, WC;VERTER, JI
通讯作者：
VERTER, JI
血清 MB 肌酸磷酸激酶活性升高在诊断急性心肌梗死中的特异性。
影响因子：
2.8
作者：
R. Roberts;K. S. Gowda;P. Ludbrook;B. Sobel
通讯作者：
B. Sobel
影响因子：
37.8
作者：
GELTMAN, EM;EHSANI, AA;SOBEL, BE
通讯作者：
SOBEL, BE
急性“轻度”心肌梗塞的神话。
影响因子：
39.2
作者：
J. Madias;R. Gorlin
通讯作者：
R. Gorlin
急性心肌梗塞后的肌红蛋白血症。
DOI：
10.1016/0002-9343(75)90567-7
发表时间：
1975
期刊：
The American journal of medicine
影响因子：
--
作者：
L. Kagen;S. Scheidt;L. Roberts;A. Porter;H. Paul
通讯作者：
H. Paul