Genetic profile of a multi-ethnic population from Guine-Bissau (west African coast) using the new PowerPlex® 16 System kit
Genetic profile of a multi-ethnic population from Guine-Bissau (west African coast) using the new PowerPlex® 16 System kit
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DOI：
10.1016/s0379-0738(02)00204-9
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发表时间：
2002-09-10
影响因子：
2.2
通讯作者：
Brehm, A
中科院分区：
文献类型：
--
作者：
Gonçalves, R;Jesus, J;Brehm, A
在来自西非海岸国家几内亚比绍的无关男性样本中，测定了Promega的Powerplant（R）16 System试剂盒中包含的15个染色体STR基因座的等位基因和单倍型频率。所有人都要接受面谈，以确保他们的祖先属于同一族裔群体。这样，我们就可以发现种族间可能存在的差异。PowerRisk 16包括以前未在任何多族裔人口中研究的可疑交易报告。该试剂盒包括两个新的等位基因标记（Penta D和Penta E），这是非常有用的法医学或人口遗传学研究。几内亚人口与其他非洲人口相比有很大差异。
Allele and haplotype frequencies of 15 chromosome STR loci included in the kit PowerPlex((R)) 16 System from Promega, were determined in a sample of unrelated males from Guine-Bissau, a country from the west African coast. All individuals were subjected to an interview in order to make sure that their ancestors belonged to the same ethnic group. This way we intended to look for possible inter-ethnic differences. PowerPlex 16 includes STRs not studied before in any multi-ethnic population. The kit includes two new allele markers (Penta D and Penta E), which are very useful either in forensics or population genetic studies. The Guinean population presents significant differences when compared with other African populations.