Clustering of perirhinal neurons with similar properties following visual experience in adult monkeys
Clustering of perirhinal neurons with similar properties following visual experience in adult monkeys
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DOI：
10.1038/80664
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发表时间：
2000-11-01
影响因子：
25
通讯作者：
Desimone, R
中科院分区：
文献类型：
--
作者：
Erickson, CA;Jagadeesh, B;Desimone, R
早期视觉区域的功能组织似乎很大程度上是在发育过程中决定的。然而，对于学习和记忆重要的区域（例如鼻周皮层）的组织在成年人中可能是可以改变的。为了验证这一假设，我们记录了猕猴观察多种复杂刺激时鼻周皮层的成对神经元的情况。对于新的刺激，附近神经元对和相距较远的神经元的神经元反应偏好是不相关的。然而，经过一天的刺激体验后，附近神经元的反应偏好变得更加相似。我们得出的结论是，特定的视觉体验会诱导具有相似刺激偏好的鼻周神经元簇的发育。
The functional organization of early visual areas seems to be largely determined during development. However, the organization of areas important for learning and memory, such as perirhinal cortex, may be modifiable in adults. To test this hypothesis, we recorded from pairs of neurons in perirhinal cortex of macaques while they viewed multiple complex stimuli. For novel stimuli, neuronal response preferences for pairs of nearby neurons and far-apart neurons were uncorrelated. However, after one day of experience with the stimuli, response preferences of nearby neurons became more similar. We conclude that specific visual experience induces development of clusters of perirhinal neurons with similar stimulus preferences.