Incidence of Kawasaki disease in northern European countries.
Incidence of Kawasaki disease in northern European countries.
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DOI：
10.1111/j.1442-200x.2012.03692.x
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发表时间：
2012-12
期刊：
影响因子：
--
通讯作者：
Burns JC
中科院分区：
文献类型：
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作者：
Salo E;Griffiths EP;Farstad T;Schiller B;Nakamura Y;Yashiro M;Uehara R;Best BM;Burns JC
我们试图比较北方欧洲三个国家和日本的川崎病（KD）的流行病学特征。数据来自1999 - 2009年芬兰、挪威和瑞典医院的出院数据库，以及1998 - 2008年日本全国流行病学调查。每个国家的年发病率是使用区域普查数据计算的。在11年期间，三个北方国家的登记处记录了1，390名KD患者。每10万名5岁以下儿童的年平均发病率为：芬兰11.4，挪威5.4，瑞典7.4。总体而言，86.4%的日本KD患者小于5年，而在四个北方欧洲国家中仅为67.8%（p <0.001）。在研究期间，北方的KD发病率保持不变，远低于日本。北方欧洲和日本KD患者之间存在显著的年龄差异，这一差异仍无法解释。
We sought to compare the epidemiologic features of Kawasaki disease (KD) in three Northern European countries and Japan. Data were obtained from discharge databases for hospitals in Finland, Norway, and Sweden from 1999–2009 and from nationwide epidemiologic surveys in Japan from 1998–2008. Annual incidence for each country was calculated using regional census data. During the 11-year period, 1,390 KD patients were recorded in the registries of the three Northern European countries. Average annual incidence rates per 100,000 children less than 5 years were: Finland 11.4, Norway 5.4, and Sweden 7.4. Overall, 86.4% of Japanese KD patients were less than 5 years compared to only 67.8% in the four Northern European countries (p<0.001). The incidence of KD in Northern Europe was constant over the study period and much lower than in Japan. There was a significant age difference between Northern European and Japanese KD patients that remains unexplained.