Dye incorporation to enhance the laser ablation of standard and reduced-modulus bone cements.
Dye incorporation to enhance the laser ablation of standard and reduced-modulus bone cements.
复制标题
掺入染料以增强标准骨水泥和低模量骨水泥的激光烧蚀。
DOI：
10.1002/jor.1100160112
复制
发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Roberts,CJ
中科院分区：
文献类型：
--
作者：
Lee,CL;Litsky,AS;Roberts,CJ
激光消融丙烯酸骨水泥是骨水泥去除的一种替代方法，可用于骨水泥植入物翻修关节成形术。本研究探讨了在亚甲基蓝或红色染料no的加入下，使用连续波氩离子激光器（波长= 514 nm）的可行性。13增强两种类型骨水泥的消融：聚甲基丙烯酸甲酯和聚甲基丙烯酸丁酯。在功率（0.5、0.75和1.0 W）和曝光时间（30、45、60和90秒）不同的情况下，研究了六种水泥/染料组合。氩激光不能点燃未染色的聚甲基丙烯酸甲酯或聚甲基丙烯酸丁酯。然而，两种染料对两种水泥均有消融作用。红色染料在514 nm处的吸收峰比蓝色染料强。在所有测试水平上，红色聚甲基丙烯酸甲酯比蓝色聚甲基丙烯酸甲酯消融面积更大（p < 0.013）。红色的消融区域大于蓝色的聚甲基丙烯酸丁酯水泥。在所有测试的能量水平下，蓝色聚甲基丙烯酸丁酯水泥比蓝色聚甲基丙烯酸丁酯水泥产生更大的消融区域，周围的损伤区域更小。红色聚甲基丙烯酸丁酯水泥也比红色聚甲基丙烯酸丁酯水泥产生更大的消融面积（0.75 W和1.0 W），损伤面积也更小。在所有测试水平下，红色聚甲基丙烯酸丁酯水泥的损伤区域最小。这些结果表明，通过使用染料选择性地改变骨水泥的吸收特性，激光消融可以成为一种有效的骨水泥去除方法。水泥化学结构的变化也会影响对激光治疗的反应。此外，可以改变骨水泥的吸收光谱以最大限度地在不被骨组织吸收的波长处吸收能量；这有可能使翻修手术对骨的损伤降到最低。
Laser ablation of acrylic bone cement is an alternative method of cement removal that can be used during revision arthroplasty of cemented implants. This study investigated the feasibility of using a continuous‐wave Argon ion laser (wavelength = 514 nm) with the addition of methylene blue or red dye no. 13 to enhance the ablation of two types of bone cements: polymethylmethacrylate and polybutylmethylmethacrylate. Six cement/dye combinations were studied while power (0.5, 0.75, and 1.0 W) and exposure times (30, 45, 60, and 90 seconds) were varied. The Argon laser was unable to ablafre undyed polymethylmethacrylate or polybutylmethylmethacrylate. However, ablation was shown for both cements with either dye. The red dye had a stronger absorption peak at 514 nm than did the blue dye. Statistically larger ablation areas were seen for red polymethylmethacrylate than for blue polymethylmethacrylate (p < 0.013) at all levels tested. Ablation areas were larger in red than in blue polybutylmethylmethacrylate cement. Blue polybutylmethylmethacrylate cement produced larger ablation areas than did blue polymethylmethacrylate cements at all energy levels tested, with smaller surrounding damage areas. Red polybutylmethylmethacrylate cement also produced larger ablation areas than did red polymethylmethacrylate cement (at 0.75 and 1.0 W), again with smaller damage areas. Damage zones were smallest in red polybutylmethylmethacrylate cements at all test levels. These results suggest that, by using dyes to selectively alter the absorption characteristics of bone cement, laser ablation can be an effective method for cement removal. Changes in the chemical structure of the cement can also influence the response to laser treatment. Furthermore, the absorption spectra of the bone cement can be altered to maximize energy absorption at a wavelength that is not absorbed by bone tissue; this potentially minimizes damage to bone during revision surgery.