Yucatan pig: An optimal hairless model for a true random cutaneous flap
Yucatan pig: An optimal hairless model for a true random cutaneous flap
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DOI：
10.1007/s002669900111
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发表时间：
1997-05-01
影响因子：
2.4
通讯作者：
Guyuron, B
中科院分区：
文献类型：
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作者：
DeLuca, L;Beckenstein, M;Guyuron, B
由于猪和人类皮肤血液供应的相似性，猪模型已被广泛用于皮瓣研究。尤卡坦小型猪提供了一个很好的模型，研究的性质，随意皮瓣，提供了几个优势，比其他品种的猪。在这项研究中，共67个随机的背侧皮瓣测量4 × 14厘米的9尤卡坦小型猪提出。非延迟皮瓣的平均存活长度（10.03 ± 1.60 cm）大于文献报道的其他皮瓣。皮下组织和肉脂膜之间的良好定义的平面促进了皮瓣始终在肉脂膜水平上方的提升，从而确保了真正的随机皮瓣的创建。此外，皮肤的无毛性质，特别有利于研究化学脱皮，允许容易可视化和监测任何外部皮肤变化。这些优点使尤卡坦小型猪成为皮瓣研究中其他猪种更理想的替代品。
Porcine models have been used extensively for skin flap research because of the established similarity between the cutaneous blood supply of the swine and humans. The Yucatan minipig provides an excellent model for researching the properties of random cutaneous flaps, offering several advantages over other breeds of swine. In this study, a total of 67 random cutaneous dorsal flank flaps measuring 4 x 14 cm were raised on nine Yucatan minipigs. The mean survival length (10.03 +/- 1.60 cm) of the nondelayed flaps was greater than others reported in the literature. The well-defined plane between the subcutaneous tissue and the panniculus carnosus facilitated flap elevation consistently above the level of the panniculus carnosus thereby ensuring the creation of a true random cutaneous flap. Furthermore, the hairless nature of the skin, particularly beneficial in studying chemical peels, permits easy visualization and monitoring of any external skin changes. These advantages make the Yucatan minipig a more desirable alternative to other breeds of swine for use in skin flap research.