Nucleocytoplasmic transport: Driving and directing transport

Nucleocytoplasmic transport: Driving and directing transport
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DOI:
10.1016/s0960-9822(98)70239-8
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发表时间:
1998-05-21
期刊:
影响因子:
9.2
通讯作者:
Hammell, CM
Hammell, CM
中科院分区:
生物学1区
文献类型:
--
作者:
Cole, CN;Hammell, CM

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核质运输涉及与小的GTP酶Ran相互作用的货物-受体复合体的组装和跨核移动。RAN调节蛋白RanGAP1和RCC1的不对称分布为核运输提供了驱动力和方向性。(C)现代生物有限公司ISSN 0960-9822。
Nucleocytoplasmic transport involves assembly and movement across the nuclear envelope of cargo-receptor complexes that interact with the small GTPase Ran. The asymmetric distribution of Ran regulator proteins, RanGAP1 and RCC1, provides the driving force and directionality for nuclear transport. (C) Current Biology Ltd ISSN 0960-9822.